Nature-inspired algorithms are becoming popular among researchers due to their simplicity and flexibility. The nature-inspired metaheuristic algorithms are analysed in terms of their key features like their diversity and adaptation, exploration and exploitation, and attractions and diffusion mechanisms. The success and challenges concerning these algorithms are based on their parameter tuning and parameter control. A comparatively new algorithm motivated by the social hierarchy and hunting behavior of grey wolves is Grey Wolf Optimizer (GWO), which is a very successful algorithm for solving real mechanical and optical engineering problems. In the original GWO, half of the iterations are devoted to exploration and the other half are dedicated to exploitation, overlooking the impact of right balance between these two to guarantee an accurate approximation of global optimum. To overcome this shortcoming, a modified GWO (mGWO) is proposed, which focuses on proper balance between exploration and exploitation that leads to an optimal performance of the algorithm. Simulations based on benchmark problems and WSN clustering problem demonstrate the effectiveness, efficiency, and stability of mGWO compared with the basic GWO and some well-known algorithms.

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Background:This article describes a new bone transport technique for femoral and tibial bone defects using lengthening nails combined with locking plates. We term it plate-assisted bone segment transport (PABST).Methods:Nine patients with five femoral and four tibial bone defects from open fractures or malignancies were treated between 2016 and 2018. Mean femoral defect length was 9.3 cm (range 7 to 11.5). Mean tibial defect was 8.9 cm (range 4.8 to 15). The patients were evaluated for time to weight bearing, consolidation index, mechanical axis deviation, and limb length discrepancy.Results:Seven of nine patients have fully consolidated. The mean consolidation time was 6.6 months. The consolidation index was 0.9 (femur) and 1.26 (tibia) mo/cm. Two patients required supplementary lengthening. One patient had mild varus, one mild valgus; the remainder had a normal mechanical axis. Limb length discrepancy remained acceptable in all patients. The main complications were heterotopic ossification, delayed healing, and reduced knee motion.Conclusion:Bone transport with lengthening nails and locking plates is an effective and patient-friendly way of treating bone defects, eliminating the adverse effects of external fixation and reducing treatment time. The plate provides stability during transport and docking; it can address concomitant fractures and facilitates acute shortenings.