PurposeStatin potentially improved outcome in patients with COVID-19. Patients who receive statin generally have a higher proportion of comorbidities than those who did not, which may introduce bias. In this meta-analysis, we aimed to investigate the association between statin use and mortality in patients with COVID-19 by pooling the adjusted effect estimates from propensity-score matching (PSM) matched studies or randomised controlled trials to reduce bias.MethodsA systematic literature search using the PubMed, Scopus and Embase databases were performed up until 1 March 2021. Studies that were designed the study to assess statin and mortality using PSM with the addition of Inverse Probability Treatment Weighting or multivariable regression analysis on top of PSM-matched cohorts were included. The effect estimate was reported in term of relative risk (RR).Results14 446 patients were included in the eight PSM-matched studies. Statin was associated with decreased mortality in patients with COVID-19 (RR 0.72 (0.55, 0.95), p=0.018; I2: 84.3%, p<0.001). Subgroup analysis in patients receiving statin in-hospital showed that it was associated with lower mortality (RR 0.71 (0.54, 0.94), p=0.030; I2: 64.1%, p<0.025). The association of statin and mortality was not significantly affected by age (coefficient: −0.04, p=0.382), male gender (RR 0.96 (0.95, 1.02), p=0.456), diabetes (RR 1.02 (0.99, 1.04), p=0.271) and hypertension (RR 1.01 (0.97, 1.04), p=0.732) in this pooled analysis.ConclusionIn this meta-analysis of PSM-matched cohorts with adjusted analysis, statin was shown to decrease the risk of mortality in patients with COVID-19.PROSPERO registration numberCRD42021240137.

No abstract

Abstract. Susandarini R, Khasanah U, Rosalia N. 2021. Ethnobotanical study of plants used as food and for maternal health care by the Malays communities in Kampar Kiri Hulu, Riau, Indonesia. Biodiversitas 22: 3111-3120. Studies to reveal the diversity of food plants on communities living in remote areas with limited access to the market are important as an effort in documenting the traditional knowledge. The same applies to the diversity of medicinal plants used in maternal health care for communities that have limited access to public health facilities. The documentation of ethnobotanical knowledge is not only for the purpose of developing the potential of these plants, but also could have an impact on their conservation in nature. This study aims to document the traditional knowledge on the diversity of food plants and medicinal plants used in maternal health care by Malays tribes living within the Bukit Rimbang Bukit Baling Wildlife Reserve, Kampar Kiri Hulu Subdistrict, Kampar District, Riau Province, Indonesia. The research was conducted in three villages by collecting data through interviews and followed by fieldwork to collect plant specimens for identification. Data on food plant diversity data were obtained from 20 informants, while data on the diversity and use of medicinal plants for maternal health care were obtained from 73 informants. The results showed that there were 76 species of food plants from 35 families. These food plants were used as secondary food ingredients, vegetables, fruit and spices with most of these plants were obtained from the yard of the house. Plants used for maternal health care identified from this study were 34 species from 26 families. These plants were used for various purposes during pregnancy, child delivery, postpartum recovery, and infant health care. The diversity of food plants and medicinal plants for maternal health care documented in this study showed the valuable role of plant resources in supporting daily needs and health care of the communities living in the fringe of forest area.

<p class="06IsiAbstrak"><span lang="EN-GB">Artikel ini menjelaskan tentang bagaimana kita memahami sebuah hadits dengan menggunakan kajian <em>Ma’anil Hadits </em>yaitu ilmu yang mengkaji tentang bagaimana memahami hadits Nabi Saw dengan mempertimbangkan berbagai aspek. Dengan tujuan untuk mengetahui bagaimana kualitas hadits tentang wudhu ditinjau dari aspek sanad dan matannya. Dan untuk mengetahui bagaimana pemahaman hadits (<em>fiqh al-hadits</em>) tentang urgensi wudhu dan relevansinya bagi kesehatan dalam perspektif Imam Musbikin. </span></p><p class="06IsiAbstrak"><span lang="EN-GB">Dan setelah diteliti dengan menggunakan metode takhij al-hadis bahwa hadits-hadits yang diteliti, baik secara sanad maupun matan dapat dikatakan hadits tersebut sebagai hadits yang <em>shahih </em>baik <em>shahih al-isnad </em>maupun <em>shahih al-matn </em>dan dapat dipegang sebagai riwayat yang bersumber dari Nabi Saw. Selain itu, Manfaat cara wudhu terhadap kesehatan adalah dapat membersihkan berbagai kotoran, virus, dan bakteri yang berada di telinga, hidung, mulut dan gigi, serta dapat mempermudah regenerasi selaput lendir sehingga dapat mencegah berbagai penyakit yang masuk melalui telinga, hidung dan mulut,  baik penyakit yang ringan maupun penyakit yang serius. Selain itu, kebanyakan titik refleksi berada pada anggota wudhu. Sehingga kita menjalankan wudhu tidak hanya sebatas ritual yang dilakukan sebelum sholat, karena banyak manfaat dibalik ritual tersebut jika kita melakukannya dengan benar.</span></p>

Background/Aims The coronavirus disease 2019 (COVID-19) pandemic has necessitated modifications to allow the safe practice of clinical gastroenterology and gastrointestinal endoscopy. This study aimed to investigate the characteristics of clinical gastroenterology and gastrointestinal endoscopy practices during the COVID-19 pandemic in Indonesia. Methods This cross-sectional study enrolled physician members of the Indonesian Society for Digestive Endoscopy. We used an online self-administered questionnaire disseminated via social media. The 32-item survey determined the baseline characteristics of the participants, characteristics of clinical gastroenterology and gastrointestinal endoscopy practices, involvement of the physicians in the management of COVID-19, and overall impact of the pandemic on practice. All collected data were analyzed using descriptive statistics. Results The 200 participants in this study had a median age of 50 (34–76) years. Modifications in clinical gastroenterology practice were frequently reported in the outpatient (95.5%) and inpatient (100%) settings. All participants reported changes in the gastrointestinal endoscopy practice patterns. Of the participants, 86.0% were working in high-risk zones, and several of them reported inadequate protective personal equipment (34.0%). The median overall impact score of the pandemic on practice was 9 (2–10). Conclusions Physicians practicing clinical gastroenterology and gastrointestinal endoscopy in Indonesia work in high-risk settings. Modifications in clinical gastroenterology and gastrointestinal endoscopy practices are prevalent during the COVID-19 pandemic.