The paper reveals essential features of financial and credit products as inherent components of Russian and global financial market, which is driven by current global economy integration trends. Financial market is highlighted to provide economic security and proper environment for individuals and legal entities. Taking structural fluctuations in consuming credit products as well as product extension, authors dip into this financial market segment.
Purpose. To evaluate the significance of IgG detection to glycoprotein E of varicella-zoster virus (VZV) for the infection stage diagnosis.Materials and methods. Integration of literature data.Results. Analysis of literature data allows to make quite reasonable conclusion that the dynamics of IgG antibodies to glycoprotein E of VZV is subject to the general laws of the antibody productions in the course of infectious processes, although the final completion of this discussion the essential results of direct detection of the dynamics of these antibodies in various stages and forms of the indicated infection.
In recent years, timely diagnosis of human herpes virus infection of type 6 (HHV6), especially in pediatrics, has acquired particular relevance. In the spectrum of serological diagnostics, an indirect ELISA method was used to detect IgM against HHV-6 in a study of samples of children sera (198), conditionally healthy patients (148) and donors (145). The use of ELISA IgM HHV6 is more significant for the expansion of the complex of the diagnostic study of the disease associated with primary HHV6 infection or its reactivation.
HHV-7 (Human Herpes virus type 7) is a relatively recently discovered, ubiquitous beta herpes virus. In Russia, the diagnosis of HHV-7 infection is carried out by PCR, which determines the DNA in serum or plasma, if there are clinical indications. Laboratory serological tests for HHV-7 are not performed. Currently, in the scientific literature, information on clinical studies of HHV-7 infection, its epidemiology, and its role in the etiopathogenesis of various diseases is insufficient. This article presents the results of the development of a test kit “ELISA-HHV-7-IgG”, designed to detect specific IgG to HHV-7 by enzyme-linked immunosorbent assay (ELISA). Studies of the sensitivity and specificity of the developed test kit, including potential cross-reactive samples positive for other herpesvirus infections, were carried out. In the context of serological diagnostics, we studied samples of the sera of children (n = 167) and old people (n = 238) for the presence of IgG to HHV-7 with confirmation of the results in the indirect immunofluorescence reaction and the immune blotting reaction. The research results are evidence of the possibility of using the developed test kit for serological diagnosis of HHV-7 infection.
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