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Monte Carlo treatment planning techniques provide a very accurate dose calculation compared to 'conventional' deterministic treatment planning systems. In the present work, the irradiation of the RANDO phantom with an Elekta Precise MultiLeaf Collimated rhombus-shaped photon beam is validated throughout the comparison of dose maps calculated with PLanUNC (PLUNC), a set of software tools for radiotherapy treatment planning, and with MCNP5 (Monte Carlo N-Particle transport code). PLUNC was initially coupled with MCNP5 and so exactly the same patient and plan parameters can be utilized in both dose calculation processes. The coupling of MCNP5 with PLUNC has been achieved via a series of Matlab interfaces, which extract patient and beam information created with PLUNC during the treatment plan and write it in MCNP5 input deck format. The multileaf collimator of the Elekta Precise unit was designed and validated by means of different beam sizes and shapes. A set of Computer Tomography images of the RANDO phantom was obtained and formatted. The slices are input in PLUNC, which performs the segmentation by defining anatomical structures. The Matlab algorithm developed by the authors, validated in previous works writes the phantom information in MCNP5 input deck format. Resulting dose maps are compared.

Radiation therapy treatment planning based on Monte Carlo simulation provide a very accurate dose calculation compared to deterministic systems. Nowadays, Metal-OxideSemiconductor Field Effect Transistor (MOSFET) dosimeters are increasingly utilized in radiation therapy to verify the received dose by patients.In the present work, we have used the MCNP6 (Monte Carlo N-Particle transport code) to simulate the irradiation of an anthropomorphic phantom (RANDO) with a medical linear accelerator. The detailed model of the Elekta Precise multileaf collimator using a 6 MeV photon beam was designed and validated by means of different beam sizes and shapes in previous works.To include in the simulation the RANDO phantom geometry a set of Computer Tomography images of the phantom was obtained and formatted. The slices are input in PLUNC software, which performs the segmentation by defining anatomical structures and a Matlab algorithm writes the phantom information in MCNP6 input deck format.The simulation was verified and therefore the phantom model and irradiation was validated throughout the comparison of High-Sensitivity MOSFET dosimeter (Best medical Canada) measurements in different points inside the phantom with simulation results. On-line Wireless MOSFET provide dose estimation in the extremely thin sensitive volume, so a meticulous and accurate validation has been performed.The comparison show good agreement between the MOSFET measurements and the Monte Carlo calculations, confirming the validity of the developed procedure to include patients CT in simulations and approving the use of Monte Carlo simulations as an accurate therapy treatment plan.