Proton computed tomography (pCT) is an evolving tomographic imaging modality with applications in proton and ion therapy. The method allows direct reconstruction of relative stopping power of patient tissues in a 3D-fashion. The pCT collaboration has built first experimental prototypes of pCT scanning systems [1] and has developed approaches to reconstruct proton CT images based on registering the coordinates and water equivalent path length (WEPL) of individual protons traversing the scanned volume. From these data one reconstructs the object boundary (hull) and initial image based on filtered back projection (FBP), calculates a most likely path (MLP) for each proton, and improves the initial image iteratively by solving a large linear system of equations of the form Ax = b using an iterative projection algorithm [2].
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.