Cissus quadrangularis a succulent vine belongs to Vitaceae family is widely distributed throughout tropical and subtropical regions of the world and used frequently to various disorders. The plant has been reported to contain flavonoids, triterpenoids, phytosterols, glycosides and rich source of calcium. This study aims to bring a systematic review of C. quadrangularis in various pharmacological mechanisms. Evidence from the previous studies suggested the efficacy of C. quadrangularis with antimicrobial, anti-diabetic, anti-inflammatory, anti-obesity, anti-oxidant, bone turnover, cardiovascular and hepatoprotective activities. In conclusion, Cissus quadrangularis appears worthy of pharmacological investigations for new drug formulations.

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Physalis minima Linn. was investigated for its antioxidant and acetylcholine esterase inhibition activities. The methanolic extract of the whole plant was evaluated for radical scavenging and in vitro hydrolysis of acetylthiocholine iodide. Inhibitory concentration (IC50) of the extract exhibited IC50 values of 78.6, 46.2, 76.7 and 296 μg/mL under 2,2-diphenyl-1-picrylhydrazyl (DPPH), ABTS (2,2′-azino-bis(3- ethylbenzothiazoline-6-sulfonic acid)), hydroxyl radical scavenging and acetylcholine esterase inhibition assays. GC-MS analysis revealed the presence of 11 compounds of which most of the compounds were reported with biological activities. The study suggests further investigations of P. minima for isolation, purification and characterization of valuable bioactive compounds related to their radical scavenging activity and for the treatment of neurodegenerative disease.