Objectives: Hepatitis C Virus (HCV) infection is a significant public health issue in China. In 2006, a national seroepidemiological survey of HCV showed 5.6 million people were tested with HCV positive. Although new cases with HCV infection are mandatory to report in China, it is believed that the reported information is under-reported. The objective of this study was to correctively estimate newly infected HCV cases by gender, age, and province in China from 2005 to 2013. MethOds: The Back-calculation method was used to estimate the initial number of HCV infection, based on annual HCV reported cases issued by China CDC and the incubation distribution of HCV, which was from an outbreak due to a medical accident at a county in Liaoning, China in 2012; then the Expectation Maximization (EM) algorithm was employed to obtain the optimization estimation of HCV infection. Prior to the estimation, a rate of 49.7% from Denniston's study, in which subjects were not aware that they were infected with HCV was considered in the calculation to control for the missing report. The Monte Carlo simulation was applied to calculate total numbers and their 95% CIs. Results:The estimated numbers of newly-infected HCV cases from 2005 to 2013 were nearly 3.4 million. While 57.8% of the estimated newly-infected cases were male, cases of 30 to 39 years old were the group with the highest newly-infected cases of HCV (n= 963, 304, 28.4%). The estimated newly-infected cases also showed geographic variations that north, southwest, and west were among the regions where higher numbers were found. cOnclusiOns: This is the first time to correctively estimate newly-infected HCV cases using the annual infection disease report of China CDC; however, this estimation may still be underestimated because of the low unawareness of HCV and high rate of missing report on HCV cases in China.Objectives: -This paper focuses on this knowledge gaps for informed decisionmaking and identifies key barriers in uptake PCV in India. MethOds: -Qualitative interviews were conducted with pediatricians registered with Indian Academy of Pediatrics to generate evidence on perspective and practices regarding the PCV. A multi-level stratified sampling was applied to identify pediatricians across 12 metropolitan cities. The analysis was conducted using standard qualitative techniques to identify key domains, words, phrases and concepts from respondents. Quantitative variables are reported as mean and proportions. Results: -Majority (67.7%) of pediatricians advice for PCV to all whereas 32.2% advice PCV only to those who can afford. Around half (50.8%) have no specific preference and recommend any PCV vaccine where as 28.0% recommend PCV13. Main reason for acceptance of PCV were educated and informed clients (50.8%) followed by pediatrician's advice and counseling (25.4%) whereas main reason for denial was price of vaccine (97.3). In addition, majority (74.1%) of pediatricians wanted PCV to be included into UIP whereas (17.7%) didn't and (8.0%) were not sure. cOnclusiOns: -P...

as defined by the PDC (proportion of days covered) ratio. Considering the third agent consumption of the adherent patient population, amongst PI's persistence of DRV was the highest. Assuming 60-day gaps, the 1-year and 5-year persistence was 87% and 51%, respectively, and the median was 1851 days. ConClusions: Due to the development of ARV therapies and understanding their mechanism of action and keeping in mind the perspective of patients, we conclude that the tolerability and simplification of treatment administration could be major aspects of treatment success in real-world settings.

A343diseases, age at first pap smear, pap smear frequency, use of oral contraceptives and the number of pregnancies. Results: Overall, 600 respondents were eligible for the analysis, consisting of 465 patients (44.0±16.3 years) and 135 controls (44.0±13.2 years). More than 5 sexual partners increased the risk of acquiring HPV infections up to 2.52-fold (95%CI: 1.34-4.74), while smoking or an early sexual debut (≤ 18 years) raised it by about a factor of 1.62. Higher levels of education were associated with a protective effect. The overall rate of individuals at high risk with more than 5 sexual partners and at least another additional factor corresponded to 26.3% (158 out of 600). The proportion of subjects with an average risk (respondents with less than 5 partners and at least another additional factor) amounted to 53.2% (319 out of 600). ConClusions: Analysis of risk factors can be used as part of the economic assessment of other effective HPV vaccination strategies, including an immunization programme for pre-adolescents of both sexes in Italy. PIN16A Study of A.

generation antipsychotics (SGAs) were prescribed regardless of mono-therapy or combination therapy. Risperidone [n= 17 (56.7%)] was most frequently prescribed, followed by aripiprazole [n= 7 (23.3%)] and olanzapine [n= 5 (16.7%)]. Haloperidol was the predominant first generation antipsychotic (FGA) prescribed [n= 3(10%)]. Of the patients on combination therapy [n= 12], most [n= 10 (83.3%)] were on combination of two or more SGAs. A majority [n= 18(60%)] of the patients had an unchanged outcome at the time of discharge. ConClusions: The results of the study indicate that the therapy prescribed does not meet the clinical goals for the patients. A larger study is required to assess the prescription patterns and the predictors of outcomes among schizophrenics in the Indian population. PMH80 10-Year Medication utilization trends for stiMulant, antidePressant, and antiPsYcHotic Medications in texas Medicaid cHildren aged 3 Years old or Younger