Objective:To measure serum chromium level in women with gestational diabetes mellitus (GDM) from Chennai, South India.Materials and Methods:Thirty women with gestational diabetes, 60 age matched controls. Inclusion criteria: Gestational age 22-28 weeks, age group 20-35 years.Exclusion Criteria:Gestational age beyond 28 weeks, malnutrition or presence of infection. Serum chromium was measured using inductive couple plasma emission spectrometer.Results:Serum chromium levels of women with GDM, 1.59+/-0.02 ng/ml (range: 0.16-4.0 ng/ml) were lower than in controls (4.58+/-0.62 ng/ml; range 0.82-5.33 ng/ml) (P < 0.001). However, there were no significant differences among cases and controls when subdivided by parity.Conclusions:Women with GDM from a South Indian city had lower levels of serum chromium compared to pregnant women without GDM. Studies may be done whether chromium supplementation is useful in this group of women.

Congenital single coronary artery is commonly associated with complex congenital heart diseases and manifests in infancy or childhood. But isolated single coronary artery is a rare congenital anomaly which can present as acute coronary syndrome in adults. The aim of the work is to discuss on isolated single coronary artery in two adults presenting as acute coronary syndrome. The first case underwent coronary angiography (CAG) through right radial route, but switched over to femoral for confirmation of diagnosis and due to radial spasm. An aortic root angiogram was done to rule out presence of any other coronary ostia. It revealed a single coronary artery originating from right sinus of valsalva. After giving rise to posterior descending artery branch at crux, it continued in the atrioventricular groove to the anterior basal surface of the heart and traversed as anterior descending artery. There was no atheromatous occlusive stenosis. This is R-I type single coronary artery as per Lipton classification. In the second case, angiography was completed through right radial route. It revealed a single coronary artery arising from right aortic sinus. Anterior descending and circumflex branch were originating from proximal common trunk of the single coronary artery and supplying the left side of the heart. The right coronary artery has diffuse atheromatous disease without significant stenosis in any major branch. This is R-III C type as per Lipton classification. A coronary anomaly of both origin and course is very rare. It may be encountered in adults evaluated for atherosclerotic coronary heart disease. Knowledge and understanding of anatomical types of this congenital anomaly will reduce time, anxiety, complications during CAG and cardiac surgery.

BACKGROUND: Systemic hypertension is one of the key modiable risk factors for the rise in intraocular pressure which leads to glaucoma. This study was undertaken to see the relationship between intraocular pressure and systemic hypertension in adults aged >40yrs, to diagnose ocular hypertension and its consequences at the earliest. AIM:To study the relationship between intraocular pressure and systemic hypertension among adults aged >40 yrs. METHOD: Ahospital-based cross-sectional study was done between February 2021 to November 2021. It included 50 subjects with more than ve years history of systemic hypertension. The subjects having increased central corneal thickness (>560µm), obesity and myopia were excluded from the study. The study subjects underwent routine ophthalmic examination, intraocular pressure was measured with Goldmann's applanation tonometer before pupil dilatation and blood pressure measured by sphygmomanometer after 10 minutes of rest. The variables were analysed using percentages and mean ± standard deviation. RESULTS:Intraocular pressure increases with age up to 60 years, later on intraocular pressure decreases with further increase in age. In subjects aged 40- 60years intraocular pressure increases with systemic blood pressure (p<0.001). CONCLUSION: Hypertension was a contributing factor for raised intraocular pressure in subjects aged 40-60yrs. So, routine assessment for raised blood pressure is required for screening glaucoma.

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