The aim of investigation is to study the influence of different types of anesthesia on hemostasis in proctological patients, and to develop the algorithm to determine adequate method of anesthesia to prevent hemostatic disorders. 120 patients have been investigated with new instrumental method — hemocoagulography. It has been estimated that different types of anesthesia have different influence on functional activity of hemostasis.

The research of a haemostatic system in trauma and acute haemorrhage patients by a new instrumental method — haemocoagulographia — allows at early stages of disease to reveal patients having the tendency to development haemostatic anomalies, Multi Organ Dysfunction Syndrome and failure of disease, that increases accuracy of an evaluation of weight of a condition and prognosis on APACHE-III system (Acute Physiology And Chronic Health Evaluation).

A investigation of the indices, characterizing a functional condition of the hemostasis in patients with peritonitis, to takes more reliable trend forecasting a development of the multiorgans insufficiency syndrome and unfavorable outcome of the disease, tran research of hemodynamic and autointoxication states.

The complexity of measures on detoxication of an organism is caused by the critical state of a patient against the background of multiple organ failure, disordered hemodynamics, pronounced changes of hemostasis, protein-energy deficiency, waterelectrolytic and acid-base disbalance. A new method is proposed for the treatment and control of the detoxication process. The positive effect of this method is caused by the syndrome-by-syndrome character of the therapy and the multilevel direction of the action. The proposed method involves all the interested organs and systems of an organism into the detoxication process.

The Purpose of the study investigation — a study of the influence opioid and epidural analgezium on hemostasis beside women’s in perinatal period, as well as determination of the possibility of the preventive maintenance hemostatic complications by way to optimization intranatalis anesthetizations. 90 pregnant were examined, women in childbirth and woman recently confineds by means of new instrumental method -— hemocoagulography. It is revealled that only epidural analgezium statistical realistically influences on functional condition of the system hemostasis.