This study was done to investigate epidemiological data and to report causes of lower urinary tract disease in a population of cats presented at the Small Animal Clinic of the University of Veterinary and Pharmaceutical Sciences Brno. Cats presented with lower urinary tract disease signs that had undergone a thorough physical examination and urinalysis (dipstick, urine specific gravity, urine sediment and dipslide urine culture) were included in the study. Urine samples were collected only by cystocentesis or sterile catheterization. Bloodwork, abdominal ultrasound, and abdominal radiographs were performed in 118 (66%), 170 (96%) and 9 (5%) patients, respectively. Cats that were treated with antibiotics or glucocorticoids during an episode of feline lower urinary tract disease (FLUTD) or during the foregoing month and which had undergone perineal urethrostomy or catheterization in private practice, were excluded. The study population consisted of 177 cats. Forty-one (23%) cats were diagnosed with a urethral plug, 26 cats (14%) with a urinary tract infection (UTI), 9 cats (5%) with urolithiasis and 101 cats (57%) with feline idiopathic cystitis (FIC). The cats diagnosed with UTI were significantly older than the cats with FIC, urethral plugs and urolithiasis. Urinary tract infection was diagnosed significantly more often in patients older than 10 years, and in female cats. The diagnosis of urethral plug was made significantly more often in males. Feline idiopathic cystitis and urethral plugs are the most common causes of FLUTD, and the causes are significantly age and sex-related.

No abstract

The aim of the study was to evaluate the efficacy of ketamine, dexmedetomidine, atipamezole and alfaxalone delivered by two methods of intranasal administration in terrapins. The two methods were used in 21 healthy adult female red-eared terrapins: (A) with fully extended neck and restrained head, (B) with head hidden inside the shell. Ketamine (10 mg/kg) and dexmedetomidine (0.2 mg/kg) were delivered using a micropipette in the left and the right naris, respectively. Atipamezole (2 mg/kg) was administered 60 minutes later. Heart rate, head withdrawal reflex, palpebral reflex, toe-pinch reflex on the pelvic limb and glottal control enabling the insertion of the tracheal tube were recorded at 10-minute intervals. After a washout period of six months, alfaxalone (5 mg/kg) was tested. The first measurement in the alfaxalone trial started 5 minutes after the drug was administered and continued at 10-minute intervals. Heart rate decreased significantly in response to both methods of ketamine and dexmedetomidine administration. There were no significant differences between methods in time to loss of reflexes and full recovery of reflexes. Intranasal administration of atipamezole enabled rapid return to full activity. Alfaxalone administration decreased heart rate non-significantly and did not result in loss of evaluated reflexes. Both methods of drug administration of ketamine, dexmedetomidine and atipamezole resulted in a safe form of sedation and recovery. Intranasal administration of 5 mg/kg of alfaxalone was not effective.

ABSTRACT:Tritrichomonas blagburni (previously called T. foetus) has been implicated as an aetiological agent of long-term large-bowel diarrhoea in cats in many countries worldwide. The aim of this study was to determine the presence of, and risk factors for T. blagburni among a cohort of cats living in different conditions in the Czech Republic. Samples were collected from 170 cats living in different environments. The InPouch TM TF-Feline medium method was used for diagnosis of feline trichomonosis. A single case (0.6%) with motile trichomonads identified as Pentatrichomonas hominis was found in a cat from a multi-cat household. Our study suggests that trichomonads and in particular, T. blagburni, infection may be much less common in the Czech Republic than in neighbouring countries, despite the inclusion of cats that were likely to be from higher-risk groups. A review of studies of the association of trichomonads and feline diarrhoea carried out in different countries revealed variation in the frequency of trichomonads detected. Different combinations of PCR or culture methods for screening or confirmation have been utilised, with or without species differentiation; however, this could not solely account for the variation in the occurrence between countries. From those studies where differentiation was performed, we calculated from the combined studies that T. blagburni occurred in six cats without diarrhoea (1.1%) and 47 cases with diarrhoea (5%). This finding supports an association with diarrhoea as well as the occurrence of asymptomatic cases. We note that in many studies, including our own, the occurrence of T. blagburni may well be underestimated and suggest that future studies use a combination of PCR screening of both faeces and faecal cultures, with differentiation of trichomonad species.

No abstract