The aim was to study the influence of personal factors on the index of individual biological aging in men and women of mature age who continue to work and those who no longer work. The participants were 347 people, including 212 women aged 56-65 years and 111 men aged 61-69 years. Measurement of biological age, relative biological aging index, assessment of subjective psychological age, expected retirement age, life path questionnaire. Biological age was estimated using a formula that included indicators of metabolism, the work of the cardiovascular, respiratory, and balance organ systems; a psychological health questionnaire was also used. The lowest index of relative biological aging was found in people who continued to work part-time. There is a relationship between the index of relative biological aging and one's characteristics. For men, the index was lowered by the following factors: changing the place of residence, continuing to work after retirement, a high indicator of the expected retirement age, and increased by living in a large city. For women, the index was lowered by the following factors: changing the place of residence, continuing to work after retirement, a high indicator of the expected retirement age, higher education, creative hobbies, studying after retirement.