A 38-year-old premenopausal woman presented with a mass in left breast since three years. A single palpable mass measuring 3.5 X 2.5 X 2 cm was present in upper outer quadrant of left breast. The nipple and areola were unremarkable. The FNAC of mass was performed which yielded small uniform cells with scanty cytoplasm arranged in linear dyscohesive pattern [Table/ Fig-1]. The diagnosis of lobular carcinoma was rendered. Subsequently, patient underwent modified radical mastectomy with ipsilateral axillary dissection. The formalin fixed tissue sections were processed by routine histotechnical processes and stained by Hematoxylin & Eosin. Mucicarmine stain was performed to confirm the presence and location of mucin. Immunohistochemical stains were performed for Estrogen Receptor(ER), Progesterone Receptor (PR), HER 2 / neu, E-cadherin, Chromogranin A and Synaptophysin. On gross examination, a grey white tumour measuring 3.5 X 2.5 X2 cm was seen in upper outer quadrant 0.7 cm away from the base and 0.5 cm away from the skin [Table /Fig-2a]. Ten axillary lymph nodes were dissected, largest measuring 3X3X2.5 cm. The cut surfaces of the tumour and the larger lymph nodes were glistening [Table/ Fig-2b].
Filaria is known to be one of the neglected tropical disease. There are undiagnosed cases all across country due to asymptomatic nature, prolong incubation period and late manifestation of disease, ubiquitous mosquitoes and many are complacent when it comes to prevention; in part because of apathy towards the disease and pronged time it takes to manifest itself. Moreover, it is difficult to convince people to take tablet in asymptomatic stage. In this study we have reported, A 35-year-old male patient with symptoms of chronic urinary tract infection with hematuria followed by Chyluria. Mmicrofilaria was diagnosed in laboratory investigations; treated with anti-filarial drugs. However, the chyluria was not completely cleared till the last follow up indicating to lymphovenous fistula. To make India filaria free, we do not have alternative apart from shifting Mass Drug administration program from 2 drugs (albendazole + DEC) to 3 drug (Ivermectin, DEC and albendazole) MDA strategy.
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