The lens-free shadow imaging technique (LSIT) is a well-established technique for the characterization of microparticles and biological cells. Due to its simplicity and cost-effectiveness, various low-cost solutions have been developed, such as automatic analysis of complete blood count (CBC), cell viability, 2D cell morphology, 3D cell tomography, etc. The developed auto characterization algorithm so far for this custom-developed LSIT cytometer was based on the handcrafted features of the cell diffraction patterns from the LSIT cytometer, that were determined from our empirical findings on thousands of samples of individual cell types, which limit the system in terms of induction of a new cell type for auto classification or characterization. Further, its performance suffers from poor image (cell diffraction pattern) signatures due to their small signal or background noise. In this work, we address these issues by leveraging the artificial intelligence-powered auto signal enhancing scheme such as denoising autoencoder and adaptive cell characterization technique based on the transfer of learning in deep neural networks. The performance of our proposed method shows an increase in accuracy >98% along with the signal enhancement of >5 dB for most of the cell types, such as red blood cell (RBC) and white blood cell (WBC). Furthermore, the model is adaptive to learn new type of samples within a few learning iterations and able to successfully classify the newly introduced sample along with the existing other sample types.
Digital Inline Holography (DIH) based microscopy is a well-established technique for the characterization of nano and microparticles, such as biological cells, artificial microparticles, quantum dots, etc. Due to its simplicity and cost-effectiveness, various practical solutions such as auto characterization of complete blood count (CBC), cell viability test, and 3D cell tomography have been developed. In our previous work, we demonstrated the feasibility of this system to perform complete blood count along with the auto characterization of cell-lines as well as shape and size characterization of the microparticles. However, its performance suffered due to the weak signals from some of the cells owing to their poor signatures and the presence of background noise. The auto characterization technique therein was based on the parameters determined from our empirical findings, which limit the system in terms of its cellline recognition power. In this work, we try to address these issues by leveraging an artificial intelligence-powered auto signal enhancing scheme as well as adaptive cell characterization technique. The performance comparison of our proposed method with the existing analytical model shows an increase in accuracy to >98% along with the signal enhancement of >5 dB for most cell types like Red Blood Cell (RBC) and White Blood Cell (WBC), except the cancer cells (HepG2 and MCF-7) for which the accuracy is about 84%.
In recent times electronic throttles are more and more important in automotive engines so as to achieve better fuel economy, minimum vehicle emission and good drivability. One of the major component inside an automobile engine is throttle valve. The control of electronic throttle is actually the control of movement of plate through which amount of air that enters to the combustion engine is controlled. In this paper, initially, a mathematical model is designed by considering the dynamical behavior of the electronic throttle and further transformed to a state space model. The controller is developed by employing the dynamic surface control (DSC) technique which has been derived from backstepping and sliding mode control techniques. With the help of the simulation results the effectiveness of the proposed controller are shown which prove the validity of the technique.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.