No abstract

For seven weeks, 37 overweight adults followed a hypocaloric diet based on Orthodox Fasting (OF). A hypocaloric, time restricted eating (TRE) plan (eating between 08:00 to 16:00h, water fasting from 16:00 to 08:00h) was followed by 23 Body Mass Index (BMI)-matched participants. Anthropometric, glycaemic and inflammation markers and serum lipids were assessed before and after the diets. Both OF and TRE groups demonstrated reductions in BMI (28.54 ± 5.45 vs 27.20 ± 5.10 kg/m 2 , p<0.001 and 26.40 ± 4.11 vs 25.81 ± 3.78 kg/m 2 p=0.001, respectively). Following the intervention, the OF group presented lower concentrations of total and low-density lipoproteincholesterol, compared with the pre-fasting values (178.40 ± 34.14 vs 197.17 ± 34.30 mg/dl, p<0.001 and 105.89 ± 28.08 vs 122.37 ± 29.70 mg/dl, p<0.001, respectively).Neither group manifested significant differences in glycaemic and inflammatory parameters. Our findings suggest that OF has superior lipid lowering effects than the TRE pattern.

No abstract

Given the limitations of available evidence, more studies are required before reaching definite conclusions about the effects of OF on human health.