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This study aimed to synthesize a composite material consisting of metalorganic framework based magnesium(II) and benzene-1,3,5-tricarboxylic acid (H 3 BTC) and its modification using graphene oxide (GO) and Fe 3 O 4. The obtained material (i.e., [Mg 3 (BTC) 2 ]/GO/Fe 3 O 4) was studied as a matrix for the slow release of ibuprofen. [Mg 3 (BTC) 2 ]/GO/Fe 3 O 4 matrices were synthesized ex situ with the sonochemical method (material 1) and in situ with the solvothermal method (material 2). The obtained materials were completely characterized by X-ray diffraction and Fourier-transform infrared spectroscopy. Based on scanning electron microscopy imaging, the produced materials were spherical. The presence of GO and Fe 3 O 4 in material 1 and material 2 reduced the surface area, but it increased the adsorption capacity of ibuprofen up to 94.12%. The magnetic properties of materials 1 and 2 were observed using a vibrating sample magnetometer. These results demonstrate that modification of Fe 3 O 4 nanoparticles induces paramagnetic properties in both materials. The presence of this matrix material was able to release ibuprofen up to seven times slower at pH 5.0 and 12 times slower at pH 7.4. An increase in the pH lead to an increase in the concentration of ibuprofen released to 33.31% more than at pH 5.0.

The cover image is based on the Full Paper* The novel composite material MOF‐[Mg3(BTC)2]/GO/Fe3O4 and its use in slow‐release ibuprofen by Witri Wahyu Lestari** et al., https://doi.org/10.1002/aoc.5670.***

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