An expedited method has been developed for the diastereoselective synthesis of highly functionalized alkyl-azaarene systems with good yields and high diastereoselectivities (>15 : 1 dr).

A novel catalytic enantioselective methodology based on synergistic catalysis is reported. The strategy involves: 1) the metal-Lewis-acid activation of alkylazaarenes, and 2) the secondary-amine activation of enals. Consequently, highly functionalized chiral alkylazaarenes were obtained in good yields and with reasonable stereoselectivity.

The highly enantioselective asymmetric allylic alkylation of Morita-Baylis-Hillman carbonates with bis(phenylsulfonyl)methane is presented. The reaction is simply catalyzed by cinchona alkaloid derivatives affording the final alkylated products in good yields and enantioselectivities.

The highly enantioselective asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with anthrones is presented. The reaction is simply catalyzed by cinchona alkaloid derivatives affording the final alkylated products in good yields and excellent enantioselectivities.

Recently green chemistry has attracted much attention from organic chemists due the problems that our society faces in terms of waste generation and energy consumption. For this reason cross dehydrogenative couplings (CDC) have emerged as one of the most important strategies for C−C bond formation nowadays. In our research group, enticed by the use of organocatalytic cross dehydrogenative coupling reactions and in the synthesis of fluorinated compounds, we developed a new organocatalytic methodology based on the CDC activation of tetrahydroisoquinolines followed by addition of fluoromalonates. The reaction is simply catalyzed by organic dyes (Rose Bengal) using green LED as a light source and oxygen as stoichiometric oxidant and let us to obtain the final fluorinated compounds in good yields.