Background: Neonatal sepsis contributes substantially to neonatal morbidity and mortality and is an ongoing major global public health challenge. In developed countries, this incidence of neonatal meningitis is 0.3 per 1000 live births. In developing countries, the reported incidence of neonatal meningitis is much higher at 0.8-6.1 per 1000 live births, with a mortality of 40-58%. So, this study was undertaken to estimate the incidence of meningitis in late onset sepsis.Methods: This study was conducted in out born NICU of R.N.T. Medical College, Udaipur (Raj.) from November 2016 to February 2017. All neonates between age 7 days to 28 days of life were included in the study. A sepsis screening and blood culture were sent for all neonates. All positive sepsis screen patients were taken for Lumber Puncture. CSF was examined with positive sepsis screen and high clinical suspicion of meningitis. CSF culture was sent for every patient. CT scan was done in patient with proven bacterial meningitis.Results: A total of 90 patients with suspected late onset sepsis were admitted. Most of the neonates were admitted with complain of temperature instability and poor feeding. Meningitis was observed in 55 out of 90 cases (61.11%). Out of 55 patients CSF culture was found positive in 70% cases. Most common organisms were E. coli in 50% cases, Klebsiella in 15% and Enterobactor in 10%. Mortality was around 45.5% (n=25).Conclusions: Neonatal meningitis is a major disease that results in death and significant mortality and morbidity in neonates.
Background: Chronic diseases are known to have impact on quality of life of patients as of the acne. The DLQI (dermatology life quality index) is a scale to assess quality of life of the patients with skin disease. Objectives: The present study analyses the quality of life patients with acne attending OPD of skin department, SMS hospital. Methods: A questionnaire-based prospective study was conducted among 150 patients with acne referred from department of dermatology, SMS hospital. Results: The mean DLQL score was 7.28, the question about how embarrassed or self-conscious have you been because of skin had highest whereas the question about how much has your skin caused any sexual difficulties? had lowest scores. Conclusion: Acne has moderate effect of quality of life of the patients. There is need for psychological intervention to improve the quality of life of the patients. Keywords: Acne, dermatology life quality index, quality of life.
Background: Postpartum depression is a prevalent and serious mental health issue in India. This affects not only a woman but also the development of her offspring. There is a need to find out various pharmacological and non-pharmacological treatment options available for the treatment post-partum depression. Method: This review was based on methods and results as described in the selected published articles available on PubMed and PsycINFO. We identified articles whose titles contained the following key terms in various combinations of the following: depression, depressive illness, postpartum, postnatal, treatment, prevention, therapy, pharmacotherapy, and antidepressant, the name of each antidepressant drug, hormonal therapy, estrogen, and progesterone. Results: We reviewed treatment of post-partum depression with antidepressants randomized clinical trials as well as open label studies, hormonal treatment, prevention studies randomized clinical trials as well as open label studies, alternative pharmacological treatment including omega-3- fatty acids- both for prevention and treatment. We also reviewed internet based intervention, cognitive behavioral therapy, kangaroo mother care, effectiveness of regular exercise, role of ECT and effect of rTMS in post part depression. When it’s about safety, the psychological interventions support their use in some women, pregnant and lactating women because of devoid of side effects to new born. Conclusion: Diverse pharmacological or psychological interventions options are available for treatment of postnatal depression. The most promising intervention is the focus on intensive and individualized approach.
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