Metformin (Mf) plays a major role in controlling insulin level of individuals at risk of developing diabetes mellitus. Overdose of Mf can cause lactic acidosis, diarrhoea, cough, or hoarseness, etc. These particulars point out the identification for selective and sensitive methods of Mf determination. In the present work, graphene nanoflakes-polymethylene blue (GNF-PMB) nano-composites were developed onto fluorine-doped tin oxide (SnO/F) coated glass substrates for electrochemical sensing of Mf using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The developed sensor shows quick response time (10 s), linearity as 10-10 µM, LOD (0.1 nM), and good shelf life (10 weeks). Attempts have been made to utilize this electrode for estimation of Mf in urine samples. Configured as a highly responsive, reproducible Mf sensor, it combines the electrical properties of GNF and stable electron transfer of PMB. The newly developed Mf sensor presents a promising candidate in point-of-care diagnosis.
Oral health promotion is for upliftment of oral health of community rather than an individual and has long-term impact. Since Ottawa Charter for health promotion is implemented, significant advancements have happened in oral health promotion. Under comprehensive health programs, India has been running oral health promotion programs, and these evidences are shared here. Such examples are apt learning and execution to any part of world having similarities. The chapter put forward the strategic view points to consider further oral health promotion aspects and based on the needs. The authors have gathered various examples from national programs implemented in India. The authors discuss how these programs are linked to the Oral health promotion concept. For example, National tobacco control program which currently running across many states in India, how the banning on tobacco products near school premises helped to reduce the incidence is discussed. The worldwide literature and evidences of oral health promotion strategies are explained. The evidences and strategies mentioned can be significant for another region of world. Unless published, many programs remain hidden and are loss of valuable evidences to oral health science.
The Information and Communication Technology (ICT) sector is characterized by rapid changes in technology. The innovation in the ICT has shown its benefits in not only facilitating better communications, but also in fostering development. Therefore, ensuring proper incentives to the private sector for innovation or diffusion of technology is crucial. However, incentivizing the private players may be challenging in developing countries, where majority of the population requires cheap access. Thus, this paper analyses the extent to which developing countries can ensure incentivizing the providers of technology, without failing on their commitment to provide cheap access to the poor. The paper analyses Local Loop Unbundling (LLU) and Universal Service Obligation (USO) and suggests ways to ensure adequate investment without jeopardizing access. The framework chosen in this paper is to see the changing treatment of LLU and USO in mature jurisdictions, and then analyze the viability of these policies in the socio-economic settings of developing countries. The framework also takes note of changes in the ICT technology.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.