Some new heteroleptic boron derivatives of the type OCH 2 C(CH 3 ) 2 CH 2 OBO(CH 3 )C:CHC(R):N(R′)OH [where R = CH 3 , R′ = (CH 2 ) 2 (2a); (CH 2 ) 3 (2b); CH(CH 3 )CH 2 (2c), R = C 6 H 5 , R′ = (CH 2 ) 2 (2d); (CH 2 ) 3 (2e); CH(CH 3 )CH 2 (2f)] have been synthesized by the reactions of tri-isopropyl borate with bifunctional tridentate Schiff bases and 2,2-dimethyl propane 1,3-diol in 1:1:1 molar ratio in refluxing benzene. Four isomers of corresponding heteroleptic derivatives 2a, 2b, 2e and 2f having the general formula OCH 2 C(CH 3 ) 2 CH 2 OBO(R′)N:C(R)CH:C(CH 3 )OH[where R = CH 3 , R′ = (CH 2 ) 2 (3a); (CH 2 ) 3 (3b), R = C 6 H 5 , R′ = (CH 2 ) 3 (3e); CH(CH 3 )CH 2 (3f) have also been synthesized by adopting different synthetic two-step processes. All these compounds have been characterized by elemental analyses, and their tentative structures have been proposed on the basis of IR, 1 H, 13 C, 11B NMR spectroscopic and FAB mass spectrometric studies. Schiff base ligands and their corresponding heteroleptic boron derivatives (2a-f) have also been screened for antimicrobial activities against pathogenic bacteria and fungi.

Organoboron derivatives of biologically potent β‐enamino esters of the type [Where R = CH3(1a), C2H5 (1b), C3H7(1c) and C (CH3)3 (1d)] have been prepared by the reactions of β‐enamino esters and Phenyl boronic acid [PhB (OH)2] in 1:2 molar ratio in refluxing tetrahydrofuran (THF). All these derivatives have been characterized by physico‐chemical properties, elemental analyses and molecular weight measurements. The structures of these compounds have been proposed on the basis of IR, 1H, 13C, 11B NMR spectral data and GC‐mass spectrometry. Phenyl boronic acid, β‐enamino esters and their respective phenylboronates derivatives have been screened for the antibmicrobial activities against pathogenic bacteria (B. subtilis and E. coli) and fungi (A. niger and P. peniculosum) to access their growth inhibiting potential. In addition to this, antiandrogenic effect of Ligand, LaH2 and its boron derivative (1a) has also been tested in male albino rats.

Background: The global population today stands at 7.7 billion and is expected to reach 9 billion by year 2045.1 Increasing population is a global problem today. India is the largest demographic country of the world, posses 2.4% of world land area and supports 16% of world’s population. India is going to be the highest populous country in the world by the year 2050. Aims and Objectives: The aim of the study was to assess the knowledge, attitude, and practice of contraception among antenatal women attending ANC clinic at Umaid Hospital. Materials and Methods: An observational and cross-sectional study conducted in department of Obstetrics and Gynaecology at Umaid Hospital, Jodhpur. Results: Our study revealed that majority (86%) of illiterate women not using contraceptive methods while users of contraceptive increase with education, contraception usage was found more in urban area (51%). Majority (95%) of participants had some knowledge about methods of contraception, commonly heard method was tubectomy (87%) followed by IUCD (68%), condoms (64%), and pills (61%), but this knowledge is not leading to increased practice, as only 43%participants had used contraception. Family acted as major source of information (35%) followed by health care worker (27%). Most of users accessed contraception from pharmacy (43%) followed by health center (24%). Most common reason to use contraception is to give gap between kids (33%) followed by, to prevent unwanted pregnancy (25%). Near 60% of participants agreed that husband opinion is the most important factor for choice of contraception. Conclusion: The consciousness to curb the rapid growth of population is rampant all over the world. Extensive efforts are being made in the developing countries to reduce the existing crude birth rates through the developing countries to reduce the existing crude birth rates through the development and reforms of indirect measures such as social, economic, cultural, health, and educational besides the direct programs of family planning.

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