The negative human activities occur at all levels – local, regional, national and global. The rapid transformation of the environment in recent years – climate changes, increased air emissions, pollution of water and soil, and the progressive accumulation of waste – has the significant negative effects. Therefore, traditional approaches and concepts of environmental and economic management are increasingly not sufficient to meet the challenges of today. The external environment has changed significantly and its uncertainty, mobility and aggressiveness have increased. Business-as-usual approaches and management technologies are increasingly off track. A synergistic approach offers new opportunities in the context of developing environmental safety in general and waste management in particular. The application of a synergetic approach to the theory and practice of environmental safety management, including waste management, which will combine the processes of external management and self-organization have been considered in the article. The importance of taking into account the synergetic effects in the field of waste management, due to the negative trends in this area is shown. The article reveals the features of synergetic systems and key management characteristics of such systems. It is shown that the circular economy at the macro level and the cluster at the micro level are complex nonlinear systems, for the control of which the provisions of synergetic should be applied. Different cluster structures are illustrated taking into account the increase of the synergetic effect. The development of a cluster from a single link (point of development) to an association in which all elements are interconnected by direct and feedback has been illustrated. Depending on the set of parameters, the cluster can change its content and form. The necessity of application of synergetic methods for effective waste management, in particular on a cluster basis is substantiated. The reasons due to which the synergetic effect is achieved when applying the cluster approach to waste management are determined.

In recent years, the use of a synergistic approach in the environmental safety is considered as one of the key tasks both for the reservation of the environment and the promotion of socio-economic progress. Domestic and foreign scientific schools are actively researching both the theoretical aspects of the synergistic concept and their practical application to the management of socio-economic systems. At the same time, insufficient attention is paid to the issue of applying a synergistic approach in waste management. The current state of waste management in Ukraine has been analyzed and the main reasons restraining the development of this sector have been identified (weakness of the institutional base, weakness of the control over the implementation of legislation, insufficient mechanism of financial support of waste management, etc. This allows us to conclude that there is a need to rethink approaches to waste management from the standpoint of synergies. The lack of ecologically sound waste management creates a threat to the ecological safety and sustainable development of Ukraine. With the beginning of the war, the situation has significantly worsened. The purpose of the study is to develop a system of scenario-synergistic waste management dominants, which will allow identifying the key points of efforts in waste management in order to identify new opportunities in the context of the development of environmental safety. The types of interaction between the waste sector and the environment were considered, and waste management options with the least impact on the environment were determined. The system of the dominants as the basic key elements of a complex synergistic waste management system has been created. The system of the dominants is grouped into three key blocks: administrative-organizational, legal, and financial-economic. The practical value of the obtained results is to create a foundation for determining indicators that can form the basis for modeling various scenarios with the determination of the corresponding synergistic effect at the national, sectoral, regional and local levels. The application of such models in the theory and practice of waste management will increase the efficiency of decision-making in this sector