Background/Objectives Despite influenza vaccination programs in various jurisdictions, seasonal influenza vaccine (SIV) uptake remains suboptimal among older people (�65years old), an important subpopulation for influenza vaccination. We sought to summarize determinants of SIV uptake (any vaccine receipt) and vaccination adherence (receipt of vaccine in two or more seasons in sequence) among older people. Methods We searched for population-based studies conducted in community-dwelling older people (irrespective of their health status) from 2000-2019. Two reviewers independently selected publications for inclusion. One reviewer extracted data from the included studies; a second checked the extracted data for errors. Disagreements were resolved by discussion and consensus, or a third reviewer. We were interested in the determinants of SIV uptake and vaccination adherence. Where appropriate, we pooled adjusted results using the inverse variance, random-effects method and reported the odds ratios (OR) and their 95% confidence intervals (CI).

Analysis 3.3. Comparison 3 Safe intravenous systems versus regular systems RCT, Outcome 3 Incidence of blood leakage......... Analysis 4.1. Comparison 4 Safe intravenous systems versus regular systems CBA, Outcome 1 Number of needlestick injuries..... Analysis 5.1. Comparison 5 Safe intravenous systems versus regular systems ITS, Outcome

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