Objectives: To green synthesize silver nanoparticles by using weed plant Tridax procumbens also prepare and check antimicrobial activity of silver nanoparticles impregnated bandages against one gram positive bacteria and one-gram negative. Methods: The green synthesis of silver nanoparticles was done by chemical precipitation method using Tridax leaves extract as reducing agent. Synthesis of silver nanoparticles are characterized by UV-Visible spectroscopy, Dynamic light scattering (DLS), Zeta potential analysis, Fourier transform infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and X-ray diffraction analysis (XRD) to confirm size distribution, composition and crystalline nature of silver nanoparticles. Results: The peak was shown at 446nm by UV-Vis spectrophotometer and Scanning Electron Microscopy analysis reveals the spherical -shaped nanoparticles with a mean size of 99nm. Fourier transform infrared spectroscopy proved that the phytochemicals in extract were responsible for formation of the silver nanoparticles and acted as reducing and stabilizing agent. XRD study have revealed the highly crystalline nature of nanoparticles. These nanoparticles were impregnated onto bandages and they showed appreciable inhibitory activity against Escherichia coli (6mm) and Staphylococcus aureus (2mm). Conclusion: The characterization results shown the characteristic nature of the green synthesized silver nanoparticles. Thus the green synthesis was ecofriendly and nanoparticles showed promising antimicrobial activity. These antibacterial bandages can potentially be used for treating and open and infection-prone wounds.

Indian spices always play a great role in Ayurveda and Indian medicine. So, analyzing these plants for their unknown and specialized activity is great. Nearly all the spices have some activity on the brain and CNS. Bay leaves are one of the most common culinary spices from day to day life of Indians. In this study, we have studied bay leaves for their anti-Alzheimer activity which depends on the inhibition of acetylcholine esterase and butyrylcholinesterase. For this study, fi rstly bay leaf oil was extracted by hydrodistillation. Further phytoconstituent like alpha-pinene, terpineol, 1,8-cineol, sabinene, and methyl eugenol were isolated and purifi ed by using TLC, HPLC, and column chromatography followed by fractional distillation. These isolated phytoconstituents were evaluated for their acetylcholinesterase and butyrylcholinesterase inhibition activity in scopolamine-induced rats. This study used galanthamine as a reference, and compared the anti-alzheimer activity of all isolated phytoconstituents.

Two simple, precise and economical UV spectrophotometric methods have been developed for the simultaneous estimation of Dapagliflozin and Metformin in bulk drug and marketed formulation. In simultaneous equation method, 223 nm (λmax of DAPA) and 233 nm (λmax of MET) analytical wavelengths were selected and analysis were carried out. In area under curve method, 220-229 nm (λmax of DAPA) and 229-236 nm (λmax of MET) wavelengths were selected and analysis were carried out. The method was validated using various parameters according to ICH guidelines. The low relative standard deviation values indicate good precision and high recovery values indicate accuracy of the proposed method. Assay results were in good agreement with label claim.

Sugarcane juice is liquid extract as a drinking beverage in India, possesses therapeutic value. Stability or shelf life is very less due to spoilage or degradation of sugarcane juice because of presence of simple sugar in sugarcane juice. Microorganisms like bacteria prone to degradation of sugarcane juice. Which convert sucrose into dextran as deteriorating agent. Shelf life or stability can be improved by using natural preservatives also chemical preservatives; having a therapeutic value. In this article improvement of stability of sugarcane juice by using natural preservatives such as lemon extract, ginger extract, also may be moringa extract over the chemical preservatives. Citric acid in lemon extract acts as antimicrobial agent while ascorbic acid in ginger extract both improves stability of sugarcane juice. Stabilization of sugarcane juice improved by using naturally obtained preservatives up to several days with good quality.

Sweaty feet and foot odour are common nowadays. The existence of one or more of Staphylococcus epidermis, Bacillus subtilis and Propionibacterium Acnes on foot surface may trigger the generation of isovaleric and propionic acids, which in turn can cause a distinctive odor of feet. The present study tested susceptibility of Bacillus subtilis and Staphylococcus epidermidis to various oils and oil combinations. The outcome showed that a combination of lemon oil, neem oil and tulsi oil possessed synergistic antibacterial activity. A foot deodorizing gel containing a combination of lemon oil, neem oil, and tulsi oil; a gel base was prepared and tested for stability, organoleptic performance, antibacterial activity, irritation test, and deodorizing performance. The mixture of oils was found to reduce at least 6 logs of the primary populace of B. subtilis and S. epidermidis in 10 min. The lethal effect was found for at least 60 minutes. The gel formulation decreased at least 90% of the initial population of bacteria after 1 hour of contact when checked for days 0, 15, 30 and 60. The gel formulation also showed desired properties such as clarity, pourability, consistency, spreadability, quick absorption post application, non-stickiness and non-dryness, and absence of residue. The foot deodorizing gel formulation demonstrated antibacterial efficiency against the bacteria responsible for producing a strong foot odour.