The peculiarities of the prostate remodeling caused by long-term whole-body vibration were investigated. Vibrational prostatopathy was characterized by more incident and pronounced decrease in prostate size, blurred contours, and appearance of sites with changed density (fibrosis, calcification, cysts) in central and peripheral zones of the gland. Vibrogenic prostate remodeling is determined by marked reduction of microvessel and prostatic glands, particularly in the central (periurethral) part, smooth muscle cell hyperplasia and hypertrophy, and marked fibrosis of the stroma in the absence of inflammatory cellular infiltration. Morphological data describing reduction of microvessels in the prostate caused by whole-body vibration correlate with Doppler scanning data indicating reduced perfusion of the organ.

The article provides up-to-date statistics on the prevalence of purulent pyelonephritis in Russia, shows the pathogenesis of purulent pyelonephritis in terms of circulatory disorders in the kidney for example 23 patients operated personally by the author in Urology conditions of the Altai Krai hospital on his own technique in the period 2016 by 2017. Morphological studies were carried out in the Department of pathologic Anatomy. Assess the morphological distortion in the kidney with significant changes in the mikrocirkuljatornom vein during the operation of the apostem zone, perifokalnogo zone of inflammation around 1 cm from the pockets of destruction and of apparently healthy sections of kidney the same kidney parenchyma jelektronnomikroskopicheskim method. Additionally investigated plots tissues of the kidneys removed due to have resulted them irreversible destructive changes. Irreversible development of acute purulent pyelonephritis associated with renal tissue ischemia and to achieve good results in the treatment of patients, appropriate action must be taken to restore the lost blood flow.