A case of malignant granular cell tumour (myoblastoma) which metastasized from the vulva to the regional lymph nodes is presented. Electron microscopy of the metastases demonstrated the presence of numerous intra-cytoplasmic lysosomes, a feature characteristic of these neoplasms, and the neoplasm was shown to stain strongly for carcinoembryonic antigen (CEA) using the immunoperoxidase technique. Previous reports in the literature of malignant granular cell tumours are reviewed and discussed.

An abscess of the left thigh due to a fistula between a tuberculous 5th lumbar vertebra, the sigmoid colon and the muscles and subcutaneous tissues of the left thigh is described. This appears to be a unique occurrence and was only diagnosed at post-mortem. The treatment and diagnosis are discussed.