Abstract-This research aims to synthesize and characterize of rosin-polyethylene glycol derivatives from natural rosin and polyethylene glycol 1500 (PEG1500). In this research, reaction conditions for the synthesis of rosin-PEG derivatives such as catalyst type, catalyst concentration, reaction temperature and etc. were optimized. Chemical and physical properties of water soluble rosin (WSR) were characterized using FT-IR, 13 C-NMR, DSC, and GPC. It was found that water soluble rosin-PEG derivatives were successful synthesized from natural china rosin and PEG using 2% ZnO as catalyst, 2:1 molar ratio of rosin: PEG at 250 O C for 9 hours. The obtained rosin-PEG1500 derivative were completely soluble in water and rosin-PEG1500 derivative showed melting point at 40.6Index Terms-Water soluble rosin, polyethylene glycol 1500, esterification, zinc oxide.