IL-17 plays a major protective role against fungal infection in mice and humans. Genetic defects involving IL-17 increase the susceptibility to candidiasis. Objective: This study aimed at assessing the association between serum Interleukin-17A (IL17A) and candida infection in Intensive Care Unit patients with candidemia versus non-candidemic patients. Methodology: 90 individuals were included; 60 ICU patients, divided into 2 groups; group1: 30 patients with Candidemia, group 2: 30 patients with Candida in sputum and/or urine samples and 30 apparently healthy as a control group. All enrolled individuals underwent history taking, physical examination, laboratory assessment for Candida albicans infection and serum IL-17A. Results: IL17A level was significantly high among candidemia group ( 0.24  0.10 pg/ml) followed by group of candida in urine and sputum (0.08  0.02 pg/ml) (P-value <0.001). Conclusion: There was an association between IL-17A levels and candidemia suggesting its predictive value for a forthcoming invasive candidiasis. METHODOLOGYThe present study was conducted on 90 cases along the period between September 2015 and November 2016 after the approval of the Moral Committee of Benha College of Medicine. Each enrolled individual was guaranteed an explanation regarding the rationale,

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