This study is designed to determine the cognitive impairments in individuals with Down syndrome. This study was conducted in September to November 2014. Sample of 30 patients was taken by using purposive sampling technique within three months. Observational and Cross-sectional study design was used. This was a hospitalbased study in which patients with Down's syndrome between the age range of 5-18 and both genders were included. A structured questionnaire was developed that was based on Piaget's theory of cognitive development to assess the cognitive abilities by assessing tasks related to developmental ages. Out of those 30 patients 15(50٪) were male and 15(50٪) were females. Most of the patients were found in age range of 5-10 years according to frequency 16 (53.3٪) followed by 10 (33.3٪) patients in 10-15 years and 4 (13.3٪) in 15-20 years. The preoperational stage of cognitive development showed that the girls were more impaired. Pretend-play (boys (50%), girls(46.7%)),Centration(boys(40.%), girls(33.3%) and irreversibility boys (50%) girls(40.%) are the aspects in which boys were tending to show better than boys. In concrete operational stage and in formal operational stage both genders were tending to show equal impairments in their cognitive aspects. In the children with Down syndrome it is observed that there is high frequency of cognitive impairment and girls are more cognitively impaired than boys. While the tasks which require more accuracy and intelligence such as reasoning, meta-cognition, inductive and deductive reasoning are rarely present in both genders.

Objective: Rheumatoid Arthritis [RA] is a chronic, systemic, autoimmune disease on an unknown aetiology. It leads to the progressive destruction of joints. It also warrants difficulties in performance of Activities of Daily Living(ADL). This study aimed at determine relationship between activities of daily living [ADL] and functional status of the hand. Methods: This Crossectional Study was conducted at Romatology Department Children Hospital and Sheikh Zayed Hospital Lahore from June 2018 to December 2018. Convenient sampling technique helped in the collection of data. A hand function questionnaire and the Barthel Index were the contributary data collection methods. Rheumatoid Arthritis [RA] patients selected were those experiencing functional impairment in hands, having difficulty in performing ADL. Results: The patients who were able to perform the hand function test were independent in their daily life activities. Whereas, those who were not able to perk the test were dependent on their daily life activities. Conclusion: It was found that children with RA had a significant association between performing the ADL and functional status of hand. Key Words: Activities of Daily Living [ADL], Rheumatoid Arthritis [RA] How to cite: Ikram A.H., Ahad A.W., Huma Fazlia. Hand's functional status of children with rheumatoid arthritis in everyday activities: a cross-sectional study Esculapio. 2021.17(01): 9-14

Speech is the verbal mean of producing language & Language is the conceptual processing of communication. Children are considered to have speech delay if their speech development is considerably below the norm for children of same age.

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