Background: Ageing process can cause some changes in body system controlling mechanism. Consequently thyroid hormone levels may show variations reflected by TSH level in elderly people, more so in females.Methods: Serum TSH level were measured in 304 apparently healthy females of Dibrugarh town, Assam. Unbound T3 and T4 were measured if TSH level was abnormal. TSH levels were compared among different age groups.Results: The prevalence of hypothyroidism was found to be 8.2% in premenopausal and 12.7% in postmenopausal women. There were more cases of subclinical hypothyroidism than clinical hypothyroidism. Difference of Mean± SEM of TSH level in these two groups was significant though there was no correlation between age and TSH level.Conclusions: The study reveals decreasing thyroid function in postmenopausal female population of Dibrugarh town.

Background: EEG or Electroencephalogram is the most important diagnostic tool to detect Epilepsy. Interictal period is the time interval between two seizure episodes of an Epileptic patient. Certain wave patterns appear in the interictal period in the EEG which might predict the onset of a seizure or may give information about the last seizure attack. The aim of the study was to know how the interictal wave patterns help in diagnosing and classifying Epilepsy casesMethods: The present study was done in the Department of Physiology in association with the Department of Neurology, Assam Medical College and Hospital, Dibrugarh, Assam from June 2014 to May 2015. 113 clinically diagnosed cases of Epilepsy were studied and analyzed through Electro-encephalogram using the internationally accepted 10-20 electrode placement method. The interictal period was enquired in the history and the wave patterns that appeared in the EEG were recorded. The EEG findings were compared with the clinical diagnosis.Results: The IEDs detected were mainly of four types: Sharp waves, Spikes, Spike and wave and Polyspikes. It was found that the sharp waves (88.89%) were the predominant waveforms in the IEDs detected and this was followed by the ‘3 Hz spike and wave pattern’. It was also seen that the ‘3 Hz spike and wave pattern’ was associated with ‘Absence seizures’. And Myoclonic seizures were associated with polyspikes.Conclusions: It is hereby concluded that certain wave patterns in EEG appear in certain types of epilepsy that can be clinically correlated for proper diagnosis of epilepsy.

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BACKGROUND EEG or Electroencephalogram, which is the most important diagnostic procedure to evaluate Epilepsy patients, may sometimes fall short of accurate sensitivity and may require few Activation Procedures such as 'Hyperventilation' and 'Sleep' to bring out the active changes of an Epileptic brain. The present study was done with the aim of knowing the efficacy of such Activation Procedures like 'Hyperventilation' and 'Sleep' in illustrating the EEG wave pattern changes of an Epileptic brain during the interictal period.