With the increasing number of flexible distributed energy resources, it is difficult for the distribution network to control various devices directly. Therefore, managing and dispatching the resources in a cluster way is required. This article proposes an equivalent model‐based asynchronous dispatch framework, which is composed of three layers, the distribution network, clusters, and distributed energy resources. With this framework, economic dispatch is carried out with the equivalent models of clusters, simplifying the dispatch problem of the distribution network. The numerical test results show that the proposed method can significantly reduce the calculation time and maintain high accuracy in the economic dispatch problem.