R ED radish sprouts (RRS) (Raphanus sativus) are rich sources of health-promoting phytochemicals more than in its seeds.The present study aimed to evaluate the protection efficiency of red radish sprouts as hypocholesterolemic and antiobesity agents in adult females. Forty-five females with body mass index (BMI) ˃28 and aged between 25 and 40 years were randomly divided into three groups each one containing 15 females; RRS group and the controls. G1 (the first control) consumed their usual diet, while the second control group includes participants who were subjected to a low-calorie diet individually. The third group includes participants who were subjected to a low-calorie diet with RRS (100 g per day). Participants were initially submitted to anthropometric measurements (weight, body fat %, height, waist circumference, and mid-upper arm circumference ), and blood samples for analysis of serum glucose, lipid profile (total cholesterol, HDL-c, LDL-c, and triglycerides) AST, ALTand TSH levels, total protein, and serum albumin. Then the groups started the intervention protocol lasting 8 weeks. After an 8-week follow-up period, the study results showed that the consumption of RRS significantly (P ≤ 0.05) suppressed the elevations in body weight (~12 %), serum cholesterol (~27.5 % reduction), serum triglycerides (~33 % reduction), AST and ALT (~35 and 21 % reduction respectively) and glucose (~7 % reduction). This work reveals, for the first time, the hypolipidemic and antiobesity potential role of RRS in adult females.

Fenugreek is one of several herbal medicines whose seeds and leaves are used either as food or as drink. The present study was designed to investigate possible potential hepatocurative & hepatoprotective activity of 5% and 10% of fenugreek (Trigonellafoenumgaraecum) seeds against cisplatin (5mg/kg body wt.) induced oxidative liver damage in male albino rats. The experimental protocol designed as the animals(42 rats) were divided into seven groups including both curative and protective groups (six rats each) : Group (1) Negative control group was fed on basal diet only for 28 days and curative groups including subgroups (2,3,4) were injected interaperitoneal by cisplatin (5mg/kg body wt.) from the first day and waiting for 24 hours to induce hepatotoxicity as follows: curative Positive control group (subgroup 2) was fed on basal diet after injection, subgroup (3,4) was fed basal diet +5% and 10% fenugreek seeds powder respectively after injection by cisplatin. While Protective groups including subgroups (5,6,7), they were injected with cisplatin interaperitoneal on the last day of the experiment and kept 24 hours after injection and divided as follows : protective Positive control group (subgroup 5) was fed basal diet and given cisplatin interaperitoneal injection (5mg/kg body wt.) on the last day of experiment. Subgroups ( 6) and ( 7) were fed basal diet and given fenugreek seeds 5% and 10% respectively and they were injected with cisplatin interaperitoneal on the last day of the experiment , then all rats were fasted overnight (12 hours), sacrificed and blood samples were collected to determine chemical analysis (AST, ALT, ALP, total protein, albumin, globulin, Albumin/Globulin, MDA, SOD, CAT. Besides, nutritional and biological parameters were recorded (FI, BWG%, FER). The results showed that fenugreek seeds powder at 5% and 10% intake in curative and protective groups improved feed intake, the body weight gain, feed efficiency ratio, liver function, and antioxidant enzymes compared with positive control groups (injected with cisplatin). It can be concluded that fenugreek seed improved the activities of liver functions and antioxidant enzymes against cisplatin that induced oxidative liver injury.

This study was designed to investigate the effect of lemongrass powder and Orlistat on hyperlipidemia in rats fed on a high fat diet. Twenty four normal male albino rats of Sprague Dawley Strain weighing (15010g), were used in this study and split into 4 equal groups; each group contained 6 rats.One group was conserved as a control negative group (G1), while (G2) were fed on high fat diet, (G3)were fed on high fat diet plus7.5 % lemongrass powder and (G4) fed on high fat diet plus Orlistat (60 mg /Kg body weight). At the end of the experiment, glucose levels, total protein (Albumin and globulin), serum liver functions, and serum lipids were assessed. The results indicated that tests plants improved glucose levels, liver functions, and lipid profile. According to these results, moderate amounts of lemongrass in our diets could be tried for improvement of hyperlipidemic humans.