This study aims to determine the effect of using mind-based quantum learning models and reading interest in argumentation writing skills of class X students of SMA 1 Linggo Sari Baganti. The theory used in this study is a quantum learning model based on mind maps, reading interest, and writing arguments. This type of research is quasi-experimental (quasi-experimental) and the design used in this study is factorial 2x2. The population of this study was class students of SMA 1 Linggo Sari Baganti. Sampling amounted to 62 uses a purposive sampling technique. The data collection was conducted through i test, consisting of tests initial ability in the form of reading and interest final ability to use performance tests for the ability to write arguments. Data analysis and discussion were carried out descriptively analysis in accordance with the concept of experimental research. First, rk verage Life Skills students taught writing argument with quantum learning model based mind map is 81.00, while students taught with the conventional model is 79.40. Second , the average argument writing skills of students with high reading interest taught with mind map-based quantum learning models is 86.25, while students with high reading interest taught with conventional models are 84.4. Thirdly, leverage writing skills argumentation low reading interest of students taught by quantum learning model based mind map is 75.75, while a low reading interest of students who are taught by the conventional model is 74.4. Fourth, there does not influence the interaction between the model of learning by reading interest towards learning outcomes k Life Skills write arguments in class X