The purpose of this study was to analyze the willingness to pay contributions of informal workers and the factors that affect the willingness to pay contribution of  Badan Penyelenggara Jaminan Sosial (BPJS) Kesehatan for informal workers in Brebes Regency. Descriptive research with quantitative approach method is used in this study. Data analysis method uses logistic regression method. The results showed that 71 respondents were willing to pay contribution of Badan Penyelenggara Jaminan Sosial (BPJS) Kesehatan for the sustainability of the program and improve the quality of service facilities and 29 respondents said they were not willing to pay. Factors that have a significantly affect on willingness to pay for informal workers are income variable, number of family members, and history of catastrophic disease. Whereas the factors that have no significant on willingness to pay are the last education variable and knowledge. The policy implication for local governments is to increase productivity in the informal sector which aims to increase income of informal workers and re-record Pekerja Bukan Penerima Upah (PBPU) participants who are economically incapable to be transferred to Penerima Bantuan Iuran (PBI) participants. Increase knowledge related to the importance of paying contributions to Pekerja Bukan Penerima Upah (PBPU) participants by Badan Penyelenggara Jaminan Sosial ( BPJS) Kesehatan.