Thiofluorenone 769 2-Amino-4-methyl-5-thioformamidomethylpyrimidine (XI).-To 1.8 g. (0.01 mole) of the hydrochloride of X dissolved in 5 cc. of water and cooled below 15°a solution of 1.2 g. of potassium carbonate in 4.0 cc. of water was added as rapidly as possible with cooling. A solution of 1.2 g. of potassium dithioformate in 3.5 cc. of water was added immediately and the mixture was stirred for four hours at room temperature. The solid material was isolated by filtration and washed with water. The washed product was dissolved in 8 cc. of 50 ( acetic acid and filtered from a small amount of insoluble material. The warm solution was neutralized with ammonium hydroxide (sp. gr. 0.89), cooled, and filtered. The dried solid, which had a slightly green east, weighed 1.3 g. (71%), m. p. 192-198°. After two recrystallizations from water, XI melted at 212-213°.

II (2 g.) was dissolved in acetic acid (50 cc.) and, after addition of potassium dichromate (2 g.) in acetic acid (30 cc.), heated to boiling for two minutes. Upon pouring onto ice, a yellow precipitate (1.7 g.) was obtained. It crystallized from ethanol in yellow prisms of m. p. 135-136°. An additional recrystallization from acetic acid raised the m. p. to 140-141 °, as reported in the literature.6 The yield of pure produpt was 1.2 g. (60%).

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