Addition of N -centered radicals to C=C bonds or insertion into C–H bonds is well represented in the literature. These reactions have a tremendous significance, because they afford polyfunctionalized organic molecules. Despite the tetrahydroisoquinoline (THIQ) moiety widely occurring in natural biologically active compounds, N -unsubstituted THIQs as a source of N -centered radicals are not studied. Herein, we report a photocatalytic reaction between tetrahydroisoquinoline and chalcones that gives N -fused pyrroles—1,3-disubstituted-5,6-dihydropyrrolo[2,1-a]isoquinolines (DHPIQ). The mechanism includes at least two photocatalytic events in one pot: (1) C–N bond formation; (2) C–C bond formation. In this process potassium poly(heptazine imide) is used as a visible light active heterogeneous and recyclable photocatalyst. Fifteen N -fused pyrroles are reported with 65–90% isolated yield. DHPIQs are characterized by UV–vis and fluorescence spectroscopy, while the fluorescence quantum efficiency of fluorinated DHPIQs reaches 24%.

Background: Cardiac implantable electronic devices (CIED) are very rare in the pediatric population. In children with CIED, transvenous lead extraction (TLE) is often necessary. The course and effects of TLE in children are different than in adults. Thus, this study determined the differences and specific characteristics of TLE in children vs. adults. Methods and Results:A post hoc analysis of TLE data in 63 children (age ≤18 years) and 2,659 adults (age ≥40 years) was performed. The 2 groups were compared with respect to risk factors, procedure complexity, and effectiveness. In children, the predominant pacing mode was a single chamber ventricular system and lead dysfunction was the main indication for lead extraction. The mean implant duration before TLE was longer in children (P=0.03), but the dwell time of the oldest extracted lead did not differ significantly between adults and children. The duration (P=0.006) and mean extraction time per lead (P<0.001) were longer in children, with more technical difficulties during TLE in the pediatric group (P<0.001). Major complications were more common, albeit not significantly, in children. Complete radiographic and procedural success were significantly lower in children (P<0.001).Conclusions: TLE in children is frequently more complex, time consuming, and arduous, and procedural success is more often lower. This is related to the formation of strong fibrous tissue surrounding the leads in pediatric patients.

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The optical thickness of highly attenuating packed-bed particulate media can be significantly reduced and, consequently, the radiation heat transfer enhanced, by the addition of large (>100 m) semi-transparent SiO 2 particles. The monochromatic transmittance of packed-bed mixtures of SiO 2 , ZnO, and C particles of various relative mass fractions is experimentally measured as a function of the packed-bed thickness using a He-Ne laser/fiber optic/spectrometer system. Two functions, one derived from the general solution of the equation of radiative transfer for an absorbing-scattering-non emitting medium, and a second one derived from Bouguer's law, were fitted to the experimental data and used to elucidate the effect of the incoming scattering and optical thickness on the medium transmittance. The augmenting contribution of the incoming scattering diminishes with increasing content of highly absorbing carbon particles, and, when it becomes negligible, the extinction coefficient is directly determined by applying Bouguer's law for attenuation of incident radiation along its path.

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