Controlled assembly of colloidal nanoparticles onto solid substrates generally needs to overcome their thermal diffusion in water. For this purpose, several techniques that are based on chemical bonding, capillary interactions with substrate patterning, optical force, and optofluidic heating of light‐absorbing substrates are proposed. However, the direct assembly of colloidal nanoparticles on generic substrates without chemical linkers and substrate patterning still remains challenging. Here, photothermal convection lithography is proposed, which allows the rapid placement of colloidal nanoparticles onto the surface of diverse solid substrates. It is based on local photothermal heating of colloidal nanoparticles by resonant light focusing without substrate heating, which induces convective flow. The convective flow, then, forces the colloidal nanoparticles to assemble at the illumination point of light. The size of the assembly is increased by either increasing the light intensity or illumination time. It is shown that three types of colloidal gold nanoparticles with different shapes (rod, star, and sphere) can be uniformly assembled by the proposed method. Each assembly with a diameter of tens of micrometers can be completed within a minute and its patterned arrays can also be achieved rapidly.

Programmable liposomes are designed to selectively produce various liposome-nanoparticle hybrids.

Since the invention of the atomic force microscope (AFM) three decades ago, there have been numerous advances in its measurement capabilities. Curiously, throughout these developments, the fundamental nature of the force-sensing probe—the key actuating element—has remained largely unchanged. It is produced by long-established microfabrication etching strategies and typically composed of silicon-based materials. Here, we report a new class of photopolymerizable hydrogel nano-probes that are produced by bottom-up fabrication with compressible replica moulding. The hydrogel probes demonstrate excellent capabilities for AFM imaging and force measurement applications while enabling programmable, multifunctional capabilities based on compositionally adjustable mechanical properties and facile encapsulation of various nanomaterials. Taken together, the simple, fast and affordable manufacturing route and multifunctional capabilities of hydrogel AFM nano-probes highlight the potential of soft matter mechanical transducers in nanotechnology applications. The fabrication scheme can also be readily utilized to prepare hydrogel cantilevers, including in parallel arrays, for nanomechanical sensor devices.

Mechanical metamaterials that are engineered with sub-unit structures present unusual mechanical properties depending on the loading direction. Although they show promise, their practical utility has so far been somewhat limited because, to the best of our knowledge, no study about the potential of mechanical metamaterials made from sophisticatedly tailored sub-unit structures has been made. Here, we present a mechanical metamaterial whose mechanical properties can be systematically designed without changing its chemical composition or weight. We study the mechanical properties of triply periodic bicontinuous structures whose detailed sub-unit structure can be precisely fabricated using various sub-micron fabrication methods. Simulation results show that the effective wave velocity of the structures along with different directions can be designed to introduce the anisotropy of stiffness by changing a volume fraction and aspect ratio. The ratio of Young's modulus to shear modulus can be increased by up to at least 100, which is a 3500% increase over that of isotropic material (2.8, acrylonitrile butadiene styrene). Furthermore, Poisson's ratio of the constituent material changes the ratio while Young's modulus does not influence it. This study presents the promising potential of mechanical metamaterials for versatile industrial and biomedical applications.Recent advances in the fabrication of micro-/nano-structures have resulted in the development of interesting mechanical metamaterials like phononic (acoustic) 1 and meta-fluidic materials 2 . Phononic metamaterials have a negative effective bulk modulus 3 or negative effective mass densities 4 . These properties can be used in applications like acoustic subwavelength imaging 5 , superlensing 6 , and transforming acoustics 7,8 . Meta-fluidic materials have extremely large bulk modulus compared to shear modulus, which makes them behave like a fluid 2 . Similar concepts have also been explored to improve mechanical characteristics with new designs of micro lattices without changing the chemical composition or weight 9,10 . Ultralight and ultrastiff metamaterials have been reported, which maintain a nearly constant stiffness per unit mass density even at ultralow densities 10 . Anisotropic versions of meta-fluidic materials have been suggested, which can be used in elasto-dynamic cloaking devices 11 . Wave trapping in cellular metamaterial plates constructed by bending-dominated and stretch-dominated unit-cells has been studied based on the numerical simulation 12 . The interesting mechanical properties of mechanical metamaterials are a consequence of their deliberate structuring, and not of the bulk material that comprises them. Owing to the complicated patterns involved 10,13 , currently mechanical metamaterials are mostly fabricated by using three dimensional printing. Recently, triply periodic bicontinuous structures have received attention because their geometric characteristics can be precisely controlled in the sub-micro scale with various fabrication methods...

A rapid, precise method for identifying waterborne pathogens is critically needed for effective disinfection and better treatment. However, conventional methods, such as culture-based counting, generally suffer from slow detection times and low sensitivities. Here, we developed a rapid detection method for tracing waterborne pathogens by an innovative optofluidic platform, a plasmonic bacteria on a nanoporous mirror, that allows effective hydrodynamic cell trapping, enrichment of pathogens, and optical signal amplifications. We designed and simulated the integrated optofluidic platform to maximize the enrichment of the bacteria and to align bacteria on the nanopores and plasmonic mirror via hydrodynamic cell trapping. Gold nanoparticles are self-assembled to form antenna arrays on the surface of bacteria, such as Escherichia coli and Pseudomonas aeruginosa, by replacing citrate with hydroxylamine hydrochloride in order to amplify the signal of the plasmonic optical array. Owing to the synergistic contributions of focused light via the nanopore geometry, self-assembled nanoplasmonic optical antennas on the surface of bacteria, and plasmonic mirror, we obtain a sensitivity of detecting E. coli as low as 102 cells/ml via surface-enhanced Raman spectroscopy. We believe that our label-free strategy via an integrated optofluidic platform will pave the way for the rapid, precise identification of various pathogens.