The incidence rate of malformed fetuses was 22.54% in our study group. The ultrasound detection rate was 79.02% (1062/1344). Level III prenatal ultrasound were of great value in decreasing the abortion rate of ≥ 28 gestational weeks malformed fetuses, improving malformations detection rate. The differences of the above rates between before and after level III prenatal ultrasound were of scientific value, P < 0.05. Conclusions: Level III prenatal ultrasound is important in prenatal diagnosis. It is of great help in decreasing the birth rate of malformed fetuses.

Objective: To analyze the methods of prenatal sonographic diagnosis of all kinds of aortic arch anomalies and to improve prenatal sonographic detection rate of aortic arch anomalies. Methods: 73 fetuses with congenital aortic arch anomalies were studied. The results from prenatal ultrasound examination, postnatal examination were compared. Results: 73 cases were with congenital aortic arch anomalies, 33 cases with malposition of aortic arch, 9 cases with normal left aortic arch with aberrant left subclavian artery, 5 cases with interruption of aortic arch, 26 cases with coarctation of aortic arch. The accuracy rate of prenatal sonographic diagnosis was 87.7%. Conclusions: Aortic arch anomalies have typical sonographic image. If we grasp typical sonographic images, we could make accurate diagnosis. P15.11Trends in prenasal thickness, nasal bone length and nuchal fold thickness measurements in second and third trimester Down syndrome fetuses

Poster abstracts anemia (hemoglobin 3.9 g/dl), thrombocytopenia (platelet count 21,000/mm3) and consumptive coagulopathy. With DIC and multiorgan failure, the baby was died 6 days after birth despite massive transfusion and ventilator care. Fetal MR and prenatal ultrasound imaging can be used to reveal the location, size and structural components, especially vascular components of a lesion, as well as extensiveness to the surrounding organ. It can also provide more information for differential diagnosis of vascular or soft tissue tumors. Method: Retrospective observational cohort study to assess the frequency of genetic markers and outcome of the pregnancies. Data was extracted from digitally archived ultrasound examinations and follow up was done by telephone calls to assess during the study period July 1, 2003-31 December 2007. Results: Total US genetic markers were seen 821, out of 12 511 patients (6.6%). There were 706 patients with one marker only, 74 with 2 markers and 41 patients had = / > 3 markers were present. The following 14 markers were identified: Choroid plexus cysts (CPC), Ventriculomegaly, Echogenic intra-cardiac focus (EIF), Nuchal fold (NF), Echogenic bowel, Pyelectesis/hydronephrosis, Short humerus, short femur, Single umbilical artery (SUA), Clinodactyle, Sandal gap toe, Rocker bottom foot, Omphalocele, and cystic hygroma. The total number of markers were (Number/frequency) are as follows: EIF 307 (37.4%), CPC 183 (22.3%), SUA 121 (14.7%), Pyelectesis 55 (6.7%), Echogenic bowel 51 (6.2%%), Ventriculomegaly 46 (5.6%), NF 37 (4.5%), short femur 25(3.0%), short humerus 20 (2.4%), Cystic hygroma 8 (1%), Omphalocele 5 (.6%), sandal gap toes 4 (.5%), Clinodactyle 3 (.4%), Rocker bottom feet 2 (.2%). There were 706 patients with single ultrasound markers (86%), 74 patients with 2 markers (9.0%), 41 patients with = /> 3 markers (5%). P44: SECOND AND THIRD TRIMESTER Conclusion:The frequency of ultrasound genetic markers @ Perinatal Center located in Appalachia was 6.5% and majority (86%) of patients had one marker only, 9.0% had 2 markers and 5.0% had = /> 3 markers. Outcome of all these patients was assessed on FU phone calls. Details will be presented. P44.03 Detection of birth defects by routine ultrasound in Obstetrics and Gynecology, Federal University of Mato Grosso, Cuiaba, BrazilSeventy patients had birth defects detected by ultrasonographic diagnosis in a two-year period (2004 and 2005) in Cuiaba, Brazil. Thirteen fetuses had major birth defects. The mean maternal age was 25 years and the 42% of the cases were primigravida. Only 45.7% of the patients had prenatal care. The cesarean section ratio was 58% and the frequency of autopsy was just 6%. All the affected babies were from singleton pregnancies, 9% presented with multiple defects, and 10% were stillborn. There was predominance of female babies (66%). The correlation between prenatal and postnatal diagnosis was totally reached in 81% of the cases. The most frequent ultrasound findings were from central nervous system (22%) and gastroin...