No abstract

A copper-catalyzed intramolecular cross dehydrogenative C–O coupling reaction of 2′-hydroxyl-3-arylcoumarins was developed.

Light-driven [2 + 2] cycloaddition of olefins is a kind of atom-economic and green transformation for building cyclobutane scaffolds, which are widely found in bioactive compounds and natural products. Although great progress has been made in the (dia)stereoselective synthesis of anti-cyclobutanes by photocycloadditions, the selective synthesis of syn-cyclobutanes is still full of challenges. Herein, we report a visible light-triggered and catalyst- and template-free [2 + 2] cycloaddition strategy of chalcones as a solid-state reaction in water to afford syn-cyclobutanes in high yields with excellent diastereoselectivity.

A simple and eco-friendly strategy for the synthesis of E-ortho-hydroxystilbenes from two kinds of α,β-unsaturated aromatic lactones is described.

Intramolecular oxidative CÀH amination of 2-aminobenzophenones was achieved in the presence of potassium tert-butoxide and dimethyl sulfoxide. A series of functionalized acridones were prepared in moderate to excellent yields in a mild, efficient, and transition-metal-free manner.