Purpose:influence of students' targeted and regular physical activity on their life quality. Material:in the research students (n=325, age 18-21 years) participated. Students' life quality was studied with the help of questionnaire "MOS SF-36» (J.E.Ware). We determined students' physical workability and physical fitness. Results:formation of students' physical activity was based on the worked out technology: 1) motor functioning for general endurance; 2) accent on speed-power training was made in second half of semester; 3) training of dexterity and flexibility was realized considering certain kind of academic material and future professional activity; 4) the structure of trainings in academic year included 3 stages. At first stage (September, October) 70% of time was spent for endurance, 15% -for quickness and 15% for strength. At second stage (November, March) 50% was assigned for endurance, 30% -for quickness and 20% -for strength. At third stage (April, May) 40% of time was assigned for quickness, 40% -for strength and 30% -for endurance. As a result of realization of the worked out technology for students' physical activity their individual health improved and became the factor of students' life quality perfection. Conclusions:targeted and regular physical activity of students confidently influences on their individual health by all indicators: organism's functional reserves; physical workability and fitness, way of life and organism's resistance. Targeted and regular physical activity of students facilitates improvement of students' life quality.