The aim of this study is to identify and substantiate early cognitive dysfunction in patients with brain damage in the acute period of ischemic stroke.Materials and research methods. The study included 140 elderly patients. The main group included 70 patients of Vascular Surgery Center with a diagnosis of ischemic stroke in the carotid pool, the control group consisted of 70 outpatients. Cognitive function and psycho-emotional background were assessed using the Montreal Cognitive Function Scale, tests for kinetic, constructive and ideation praxis, the Stroop test, the Boston Naming Test, the apathy rating scale, the Hospital Anxiety and Depression Scale, and the MFI-20 asthenia scale. Assessment of neuroimaging parameters was carried out usingcomputed tomography. Assessment of long-latency acoustic endogenous evoked potential P300 using the «oddball active» paradigm technique was used for neurophysiological examination.Research results. Ischemic stroke was more often detected in the parietal, frontal lobes and basal ganglia. Moderate cognitive impairment was detected in 57.5% of patients with stroke and 27.5% of the control group. Dementia was diagnosed in 30% of patients in the main group and 5% of the control group. In patients with IS indicators characterizing the executive function, praxis, speech, attention, memory, depression, and apathy were statistically significantly lower comparing with the control group. The analysis of neurophysiological data revealed a statistically significant prolongation of the latency of the P300 wave in all leads and a decrease in the amplitude of the P300 peak in leads Cz and C3 in patients of the main group. Conclusion. Within the framework of this study, significant factors in the development of early post-stroke cognitive impairment were established. Dysfunction in attention, executive function, episodic memory, and speech is the result of a combination of causes directly related to cerebrovascular disease and pre-stroke factors. The evoked potential method reflects the degree of cognitive decline and can be used as a method for assessing the effectiveness of cognitive rehabilitation in stroke patients.

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The aim of the study — to establish the severity of cognitive, psychoemotional, motivational and behavioral disorders in patients after acute period of ischemic stroke.Materials and methods. The study included 60 patients with a diagnosis of ischemic stroke. Depending on severity of neurological deficit according to the national stroke scale (NIHSS), patients were divided into two groups: group 1 — 30 patients with an NIHSS score of 0 to 8, associated with mild neurological deficit, group 2 — 30 patients with an NIHSS score of 9 to 15, associated with moderate neurological deficits. The study was conducted on the 7th day of treatment and included: assessment of the cognitive status according to the Montreal Cognitive Assessment scale; assessment of the level of distress, depression, anxiety and somatization using the Four Dimensional Symptom Questionnaire; assessment of mental and physical asthenia according to the MFI-20 scale, level of self-control using the Rotter’s Locus of Control Scale and assessment of the personality and the familial unconscious in Szondi’s test. Results. The study established the prevalence of depression and cognitive impairment in patients with moderate neurological deficits. Patients with mild neurological deficits are characterized by a moderate level of somatization, mental and physical asthenia, a low level of self-control in relation to health, low adherence to treatment and poor motivation to recover.Conclusion. The results of the study indicate the need inclusion of assessment of psychoemotional factors and personal resources of the patient in relation to illness and recovery in early diagnosis of patients with stroke. Along with neurological deficits, it is necessary to assess the cognitive, emotional and motivational levels of the “internal picture of the disease”. This can help determine the patient’s basic compensatory and adaptive capabilities and develop individual rehabilitation strategies.