This paper presents preliminary results on the fusion of denoised PET and SPECT data volumes from brushlet and wavelet thresholding methods. Texture-based brushlet denoising is well suited for enhancement of physiological information while wavelet-based denoising is better suited for enhancement of anatomical contours. A three-dimensional multi-scale edge-based data fusion algorithm is applied to combine enhanced data from these two independent denoising methods. Preliminary results with qualitative evaluation of PET and SPECT data by an expert clinician showed great potential of this approach to combine enhancement of both anatomical and physiological signal information for improved image quality.
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