An yttria-stabilized cubic zirconia (YSZ) based mixed-potential sensor coupled with CoWO 4 as the sensing electrode was developed for hydrogen detection at elevated temperatures. The developed CoWO 4 /YSZ/Pt sensor was found to have a good sensitivity to different concentrations of hydrogen from 80 ppm to 960 ppm in a background of 10% O 2 /N 2 at 450 C. The sensor showed excellent selectivity to several possible interferents such as CO, C 3 H 8 and NO 2 . The reproducibility and signal repeatability of the sensor was examined to test the reliability of the sensor. The influence of oxygen variation and humidity in the background on the sensor response was also studied.
Hyperactivity of the axis ACE/AngII/AT1R of the renin‐angiotensin system is associated with occurrence of acute thrombotic event. Recently a novel concept of a counterrugulatory axis, ACE2/Ang‐(1‐7)/Mas, has emerged. We hypothesized that ACE2 would be protective against thrombosis. Thrombus was induced in the vena cava of SHR and WKY rats by FeCl3 solution. ACE2 and ACE protein expression and activities in the thrombus were determined by Western blot and fluorogenic kinetic assays, respectively. Real time thrombus formation was visualized by intravital microscopy of the vessels of nude mice. Ferric chloride‐induced thrombus weight was 40% higher in the SHR compared to WKY rats. This was associated with a 20% decreased in ACE2 activity in the thrombus of the SHR. In contrast, ACE2 protein expression and ACE activity did not differ between the thrombus of WKY rats and SHR. Inhibition of ACE2 by DX600 increased the thrombus weight by 30%, preferentially in the SHR. Furthermore, treatment with XNT resulted in a 30% attenuation of thrombus formation in both the SHR and WKY. In addition, XNT treatment prolonged the time for complete vessel occlusion and reduced thrombus size when observed under real‐time intravital microscopy. Our data demonstrated that a decrease in ACE2 activity is associated with increased thrombus formation in the SHR. Furthermore, activation of ACE2 attenuates thrombus formation.
In this work, electrohydrodynamic atomization Layer‐by‐Layer deposition was used to deposit cathode catalyst layers (CLs) at different working distances of 3, 5, and 7 mm. The influence of working distance on the structural characteristics of cathode CLs was analyzed. The cyclic voltammograms of the cathode electrodes with different structures and the performance of the assembled membrane‐electrode assemblies (MEAs) were examined. It was observed that the cathode CLs presented well‐packed and porous features. The dispersity of the deposited catalyst and the thickness of cathode CL increased with higher working distance, which resulted in larger electrochemical active surface area (ESA), higher performance of the assembled MEAs and higher catalyst utilization. The ESA increased by approximately 70% when the cathode CL produced at the working distance of 7 mm compared with that at 3 mm. The peak power density of 56.1 mW cm–2 and the peak cathode catalyst specific power of 140.3 mW mg–1 Pt were obtained when the cathode CLs produced at the working distance of 7 mm.
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