Article is dedicated to the gallstones, cholecystectomy upon asymptomatic gallstones. Pathogenetic mechanisms of postcholecystectomical syndrome in patients after cholecystectomy without evidence are described, as well as the methods of its diagnostics. Current data on the use of drugs with a high level of evidence and recommendations in the treatment of postcholecystectomical syndrome are represented. Article also provides our own research on the improvement of the motor-evacuating function of the biliary tract and lithogenicity of the bile after cholecystectomy in patients with gallstone disease.

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This article describes the features of the course and diagnostics of gastroesophageal reflux disease in pregnant women, which is very common in this group of patients. Acceptable techniques of diagnostics of the disease are offered. Methods of non-pharmacological prevention and correction of heartburn are discussed as well. We also consider in detail the groups of drugs that are on the list of drugs allowed for pregnant women according to the FDA graduation. An analysis of drugs allowed for this group of patients that are present at the domestic market is provided.