Introduction Correct femoral tunnel position in anterior cruciate ligament reconstruction (ACLR) is critical in obtaining good clinical outcomes. We aimed to delineate whether any difference exists between the anteromedial and trans-tibial portal femoral tunnel placement techniques on the primary outcome of ACLR, graft rupture. Method Adult patients (>18 years old) who underwent primary ACLR between January 2011 - January 2018 were identified and divided based on portal technique (anteromedial v trans-tibail). The primary outcome measure was graft rupture. Univariate analysis was used to delineate association between independent variables and outcome. Binary logistic regression was utilised to delineate odds ratios of significant variables. Results 473 patients were analysed. Median age at surgery was 27 years old (range 18-70). 152/473 (32.1%) patients were anteromedial group compared to 321/473 (67.9%) trans-tibial. 25/473 (5.3%) patients sustained graft rupture. Median time to graft rupture was 12 months (IQR 9). A higher odd for graft rupture was associated with the anteromedial group, which trended towards significance (OR 2.03; 95% CI 0.90 - 4.56, p = 0.081). Conclusions There is no statistically significant difference in ACLR graft rupture rates when comparing anteromedial and trans-tibial portal technique for femoral tunnel placement. There was a trend towards higher rupture rates in the anteromedial portal group.
Embodied theories of semantic cognition predict that brain regions involved in motion perception are engaged when people comprehend motion concepts expressed in language. Left lateral occipitotemporal cortex (LOTC) is implicated in both motion perception and motion concept processing but prior studies have produced mixed findings regarding which parts of this region are engaged by motion language. We scanned participants performing semantic judgements about sentences describing motion events and static events. We performed univariate analyses, multivariate pattern analyses (MVPA) and psychophysiological interaction (PPI) analyses to investigate the effect of motion on activity and connectivity in different parts of LOTC. In multivariate analyses that decoded whether a sentence described motion or not, the whole of LOTC showed above-chance level performance, with performance exceeding that of other brain regions. Univariate ROI analyses found that the middle part of LOTC was more active for motion events than static ones. Finally, PPI analyses found that when processing motion events, the middle and posterior parts of LOTC, overlapping with motion perception regions, increased their connectivity with cognitive control regions. Taken together, these results indicate that the whole of the LOTC responds differently to motion vs. static event descriptions, and that these effects are most pronounced in more posterior sites. These findings are consistent with embodiment accounts of semantic processing, and suggest that understanding verbal descriptions of motion engages areas of the occipitotemporal cortex involved in perceiving motion.
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