Reaction of 1-dimethylaminonaphthalene-5-sulphonyl chloride with the secondary amines produced by denitrosation of N-nitrosamines yields dansyl-amides suitable for the mass spectrometric determination of Nnitrosamines. The method has been applied to the quantitative analysis of 3-4 component mixtures of N-nitrosamines. The detection limit was 1 ng with a relative standard deviation of 0.15-0.31. A gas chromatographic mass spectrometric method for the identification and quantification of mixtures of N-nitrosamines was also developed with a detection limit of 1 ng pl-' and relative standard deviation of 0.12-0.23. These methods are recommended for N-nitrosamine determination in environmental samples and have the advantage that the internal standard can be prepared directly from the respective secondary amine.

A mass spectrometric method for quantitative determination of volatile N-nitrosamines, based on analysis of the derivatives formed from secondary amines produced by denitrosation of N-nitrosamines when they are reacted with 7-chlor-4-nitrobenzo-2-oxa-1,3-diazole, is proposed. The method has been applied to the quantitative analysis of 3-4 component mixtures of N-nitrosamines without preliminary separation. The detection limit was 1 ng with a relative standard deviation of 0.13-0.25. A gas chromatographic mass spectrometric method for the identification and quantification of multicomponent mixtures of N-nitrosamines was also developed with a detection limit of 1 ng PI-' and relative standard deviation of 0.11-0.22. These methods are recommended for N-nitrosamine determination in environmental samples and have the advantage that the standards can be prepared not from carcinogenic N-nitrosamines, but directly from the respective secondary amines.