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Herein, we reported a RuCo alloy with nitrogen-doped porous carbon (RuCo/NPC) as efficient trifunctional electrocatalysts for Zn–air batteries and water splitting.

Parkinson’s disease (PD) is a complex neurodegenerative disease, manifested by the progressive functional impairment of the midbrain nigral dopaminergic neurons. Due to the unclear underlying pathogenesis, disease-modifying drugs for PD remain elusive. In Asia, such as in China and India, herbal medicines have been used in the treatment of neurodegenerative disease for thousands of years, which recently attracted considerable attention because of the development of curative drugs for PD. In this review, we first summarized the pathogenic factors of PD including protein aggregation, mitochondrial dysfunction, ion accumulation, neuroinflammation, and oxidative stress, and the related recent advances. Secondly, we summarized 32 Chinese herbal medicines (belonging to 24 genera, such as Acanthopanax, Alpinia, and Astragalus), 22 Chinese traditional herbal formulations, and 3 Indian herbal medicines, of which the ethanol/water extraction or main bioactive compounds have been extensively investigated on PD models both in vitro and in vivo. We elaborately provided pictures of the representative herbs and the structural formula of the bioactive components (such as leutheroside B and astragaloside IV) of the herbal medicines. Also, we specified the potential targets of the bioactive compounds or extractions of herbs in view of the signaling pathways such as PI3K, NF-κB, and AMPK which are implicated in oxidative and inflammatory stress in neurons. We consider that this knowledge of herbal medicines or their bioactive components can be favorable for the development of disease-modifying drugs for PD.

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-In practical power supply system, voltage always exists between neutral wire and earth wire. Excessive neutral-earth voltage in machine room will not only influence the communication and cause the increase of error rate of data transmission, but also damage network equipment. Some equipment (such as server and minimal machine) is supplied with neutral-earth voltage detection circuit. Once neutral-earth voltage exceeds a certain specified value, the equipment cannot start up. This paper mainly analyzes reasons of excessive neutral-earth voltage in machine room and puts forward corresponding solutions and specific measures.