A framing camera using pulse-dilation technology is reported in this article. The camera uses pulse dilation of an electron signal from a pulsed photo-cathode (PC) to achieve high temporal resolution. While the PC is not pulsed, the measured temporal resolution of the camera without pulse-dilation is about 71 ps. While the excitation pulse is applied on the PC, the measured temporal resolution is improved to 4 ps by using the pulse-dilation technology. The spatial resolution of the dilation framing camera is also measured, which is better than 100 μm. The relationship between the temporal resolution and the PC bias voltage is obtained. The variation of the temporal resolution with the gradient of the PC excitation pulse is also provided.
Objective: To investigate the efficacy of all-trans retinoic acid (ATRA) in human gastric dysplasia. Methods: In this double-blind study, patients with precancerous gastric dysplasia with or without intestinal metaplasia (IM) received either conventional treatment consisting of omeprazole and sucralfate (control group) or conventional treatment plus ATRA. Gastric mucosal biopsies were performed before and after drug treatment and were analysed histologically; expression of retinoblastoma (Rb) protein and HER2 protein in gastric mucosa were measured using immunohistochemistry. Results: A total of 122 patients were included in the study, 63 in the ATRA group and 59 in the control group. In the ATRA group, dysplasia was attenuated in 43 out of 63 patients (68%) compared with 22 out of 59 patients (37%) in the control group; however, IM was not affected by treatment in either group. ATRA treatment was associated with significantly increased Rb expression and decreased HER2 expression in gastric mucosa. Conclusions: The use of conventional therapy plus ATRA for gastric dysplasia was associated with improved efficacy compared with conventional therapy alone. It was also accompanied by increased Rb expression and decreased HER2 expression in gastric mucosa. The addition of ATRA to conventional therapy for gastritis may improve the prognosis of gastric dysplasia.
A chiral coordination polymer, fabricated by the rare alternate arrangement of two types of double coaxially nested helical chains, which spiral towards the parallel and inverse directions, exhibits spin-canting antiferromagnetism.Chiral coordination polymers have been paid remarkable attention in recent years, not only because of their fascinating architectures, but also for their tremendous value in enantioselective separations, nonlinear optics, asymmetric catalysis and magnetism, etc. 1 Many of the synthesized chiral coordination polymers have been found to possess beautiful helical structures, which are usually related to the occurrence of chirality. 2 Up to now, though a large number of helical coordination polymers holding single-, double-, triple-, and multiple-stranded helices have been obtained, 3 nested helical coordination polymers with the same helix axis are not common and only a few cases have been reported, 3d,4 which are constructed by encapsulation of the inner helices into the outer ones. As well, among the present cases, the inner and outer helices spiralling towards opposite directions are rare. Herein, with chiral D-camphoric acid IJD-H 2 ca) as a starting material, we have obtained a new coordination polymer ijNi 3 IJOH) 2 IJD-ca) 2 IJD-H 2 ca) 3 ] n (1), which is a chiral three-dimensional framework and exhibits spin-canting antiferromagnetism. ‡ To the best of our knowledge, Bu's group has done abundant research in the chirality field and synthesized many beautiful coordination polymers related to camphoric acid. 5 Even so, notably, compound 1 contains two types of double coaxially nested helical chains spiralling towards the parallel and CrystEngComm This journal is
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