Since 1979, housing reforms in China have been seen as successive state efforts to improve urban governance. The idea is that the state has all along failed to deliver housing efficiently and equitably through the work units and that it is believed that only through the recommodification of housing could the housing problem be ultimately resolved. The housing monetarization policy (HMP) was thus launched in 1998 to replace the long-standing in-kind housing subsidy under the old welfare housing system. The policy aims at providing workers with cash subsidies as part of their wage package to enable them to buy or rent their homes from the market. The purpose of this paper is to explain the implications of the HMP through a neoliberal urbanization perspective. Through the case study of Guiyang, it is argued that while the HMP is successful in improving certain historical housing inequalities, it does not primarily aim at eradicating housing inequalities. HMP has in fact led to more rather than less horizontal inequities. In addition, it is argued here that a market housing system is leading towards increasing urban poverty, greater social polarization and James Lee, PhD, is Associate Professor at
Background/Aims: Shikonin, a compound extracted from Zicao, has been demonstrated to hold anti-bacterial, anti-inflammatory, and anti-tumor activities in various diseases and it has been shown to protect human organs from injuries. However, the effect of shikonin on the recovery of spinal cord injury (SCI) remains unknown. This study was designed to estimate the potential therapeutic effect and underlying mechanism of shikonin on SCI in vivo. Methods: In the study, we used HE staining, ELISA assay, transfection assay, TUNEL assay, real time PCR and Western blot to detect the effects of shikonin on spinal cord injury in rats. Results: we showed that shikonin could promote the recovery of motor function and tissue repair after SCI treatment in rats SCI model. Moreover, we demonstrated that shikonin inhibited the spinal cord edema in SCI model of rats. According to further investigation, shikonin induced the reduction of inflammatory response through decreasing the expression levels of HMGB1, TLR4 and NF-κB after SCI injury. In addition, we also found that shikonin could suppress the apoptosis and expression of caspase-3 protein in SCI model of rats. Conclusion: Our results demonstrated that shikonin induced the recovery of tissue repair and motor function via inactivation of HMGB1/TLR4/NF-κB signaling pathway in SCI model of rats. Meanwhile, shikonin regulated the inflammation response in SCI by suppressing the HMGB1/TLR4/NF-κB signaling pathway. The described mechanism sheds novel light on molecular sign aling pathway in spinal cord injury and secondary injury including inflammatory response.
Fostering policy innovation at the local level and spreading the successful practice have been pervasive features of policy making in postreform China. The existing literature explains why the local government launches innovations and what enables these innovations. However, little research has been done on the emerging process of the new ideas and the process in which new policies are accepted by stakeholders. This article is an case study based on the policy innovation in the health insurance system in the city of Nanguo. We applied policy entrepreneur theory to analysis of the innovation process of the Chinese local government, with a special focus on the key agents and their interaction in the innovation process. The study reveals that bureaucrats play the role of policy entrepreneurs to elevate the rank of the organization and to acquire more administrative resources. With knowledge and technical expertise, these bureaucrats construct policy agendas; suggest innovative ideas; design policy programs; and acquire the support and approval of other stakeholders, especially local leaders, by strategies such as marketing, alliances, and fostering political achievements. By these means, they facilitate the formation and further development of the innovation policy.
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