Introduction:The quantitative parameter was successfully derived from the quantitative bone SPECT/CT images. The aim of this study was to evaluate maximum standardized uptake value (SUV) of normal structures in the head and neck with bone SPECT/CT. Methods: Fifty-three patients with jaw lesions (11 chronic osteomyelitis, eight osteoradionecrosis and 34 medication-related osteonecrosis of the jaw) who had bone SPECT/CT were prospectively included. The maximum SUV of normal structures including vertebrae, sternal body, parietal bone and hyoid bone were analysed. Statistical analyses for the maximum SUV were performed by Pearson's rank correlation test. A P value lower than 0.05 was considered statistically significant. Results: The maximum SUVs of vertebrae, sternal body, parietal bone and hyoid bone of all patients were 8.10 AE 3.72, 5.16 AE 2.05, 3.67 AE 1.55 and 1.44 AE 0.56, respectively. Furthermore, the maximum SUV of vertebrae was significantly correlated with that of sternal body (Y = 0.527X + 5.388 (R 2 = 0.084, P = 0.035)). Conclusions: Maximum SUV with bone SPECT/CT should be useful for characterization of normal structures in the head and neck. Furthermore, the data reported herein can be used for reference in future studies and in clinical settings for head and neck lesions.

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Background: In recent years, an artificial intelligence (AI) software “DentalSCOPE” for alveolar bone density based on image density of intraoral radiography was developed. Aims: The purpose of this study was to evaluate the alveolar bone density of osteoporosis patients with antiresorptive medications administration before tooth extraction using DentalSCOPE. Materials and Methods: Five osteoporosis patients with antiresorptive medications administration before tooth extraction were analyzed using a computer program “DentalSCOPE” for alveolar bone density based on image density of intraoral radiography. The alveolar bone density around extraction tooth was compared to lytic and sclerotic bone reaction with the opposite side as normal region. Statistical analyses of alveolar bone density were performed with Wilcoxon rank-sum test. P < 0.05 was considered statistically significant. Results: The alveolar bone density of the opposite side as normal region (972.9 ± 74.3 mg/cm2) was significantly higher than those of lytic bone reaction (633.9 ± 114.2 mg/cm2, P = 0.043) and lower than those of sclerotic bone reaction (1144.0 ± 99.4 mg/cm2, P = 0.043). Conclusions: This study evaluated the alveolar bone density of osteoporosis patients with antiresorptive medications administration before tooth extraction using DentalSCOPE and indicated that the computer program could be useful for the evaluation of osteoporosis patients.