pyrroles. -Best results in regard to the yield are obtained when the cyclization reaction is carried out at 0 °C. Higher temperatures give more complexe mixtures. The cyclization is not successful using other Lewis acids such as SnCl4 or ZnCl2. -(KOBAYASHI*, K.; TAKANOHASHI, A.; HIMEI, Y.; SANO, T.; FUKAMACHI, S.; MORIKAWA, O.; KONISHI, H.; Heterocycles 71 (2007) 12, 2717-2720; Dep. Mater. Sci., Fac. Eng., Tottori Univ., Koyama, Tottori 680, Japan; Eng.) -H. Haber 13-153
A simple synthesis of pyrrolo[1,2-a]quinolines carrying no substituent at all of the 1-to 5-positions based on boron trifluoride-mediated cyclization of 1-(2-oxiranylphenyl)pyrroles, which can be easily prepared from 2-(pyrrol-1yl)benzaldehydes, is described.We previously described a boron trifluoride catalyzed synthesis of 3-aminopyrrolo[1,2-a]quinolin-4-ol
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