In this manuscript, the numerical coal-rock combined bodies with different height ratios of rock part to coal-rock combined body (HRRC) were established by particle flow code (PFC) firstly, and then the influence of different HRRC on mechanical properties and numerical acoustic emission (AE) characteristics of coal-rock combined bodies were investigated. Finally, the damage constitutive model of the coal-rock combined body was discussed. The research results show that with the increase of the HRRC, the UCS and the elastic modulus (E) of the combined coal-rock bodies increased. The failure of coal-rock combined bodies is mainly focused on the coal body. The evolution law of AE hits of coal-rock combined bodies have three stages, named stable stage, rapid ascending stage, and rapid descending stage. The damage variable curves of coal-rock combined body have two stages, named slowly damage stage and sharply damage stage. The damage constitutive relation based on AE hits can well reflect the stress-strain relationships with a lower HRRC. However, for a higher HRRC, the damage constitutive equation is not accurately and the damage of the rock part in the coal-rock-combined body should be considered.

abnormal concentrations of brain metabolites and decreased glutamate plus glutamine concentration may play an important role in the pathophysiology of VRF-associated cognitive impairment. Brain metabolites detected by (1)H MRS may serve as important markers for monitoring VRFs burden.

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